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hi, my name is susan, i was diagnosed with myelitis in feb this year with a lesion at c6/7 and told i have a 50/50 chance of developing ms. i wanted to know if there was anything i could do to try to minimise this from happening? anything from lifestyle/diet etc. any advice would be more than welcome.
thank you and warm wishes to all,
susan

hi susana, welcome to TIMS and good for you for being proactive.

you might want to check out the klenner link below, in my signature.

the first best thing when undertaking nutritional approaches is to maximize your intake from a variety of healthy, nutrient dense, whole foods. be aware of food combinations that promote absorption vs food combos that interfere with absorption.

as for the protocol itself, it's a combination of oral and IV supplementation. in my view you can try oral supplements and not worry about trying to get injections, that always seemed a bit over the top to me.

if you go through the protocol in detail you'll likely end up having to make notes to figure out what you'd take at what time of day!

SUPPLEMENT BASICS:

IMHO the simplest modified version of this approach would be 10 items: 6 vitamins, 3 minerals, and a fatty acid:

VITAMINS
-decent quality multivitamin/multimineral, 1/d or as per pkg directions
-B100 complex powder capsules, up to 4/d in short term, 1/d in long term
-B12 1000mcg sublingual methylcobalamin, 1/d, PM only
-vitamin C 1000mg powder capsules, 2/d
-vitamin D3 1000 IU tablets, 4/d. some with magnesium and some away.
-vitamin E8 complex 400 IU gelcaps, up to 8/d short term, 1/d long term

MINERALS
-calcium in some form, 1000-1200mg per day
-magnesium bisglycinate or glycinate, 150-200mg capsules or tabs, 2-4/d
-zinc of some kind (mine's citrate) - 25mg powder capsules, 1-2/d

also pick up a fish oil supplement and/or lecithin, for the the fatty acids.
when fish oil shopping, look for 2:1 EPA to DHA content.

BLOODWORK:
a key thing which largely seems to be missing from klenner, with the exception of hemoglobin.

the following is a list of nutrients/indicators which are usually low in MS patients, followed by better levels more commonly seen in healthy controls.

b12 - cobalamin - aim for at least 500 pmol/L
D3 - 25(OH)D3 - min. 100 nmol/L, better up around 125 nmol/L. max 250.
zinc - high teens - avg. 18 umol/L, 17 to 19 is okay, max 30.
uric acid - aim for 290-300 umol/L. ms patients avg 194 umol/L
magnesium - aim for 0.91 mmol/L
hemoglobin - at least 13.

KLENNER REVIEW:
here are my thoughts on the various elements of the protocol:

1) Thiamin hydrochloride: 300mg to 500mg, 30 minutes before meals and bed hour...

Agree. Even 100 would be better than none.

2) Niacin (nicotinic acid): We recommend 100mg to 3 grams, thirty minutes before meals and at bed hour - whichever dose will produce a strong body flush.

Agree, in the short term. Long term high dose niacin use could have implications for the liver.

The lack of constant flushing in Multiple Sclerosis is disappointing but not hopeless. It will require a longer time to achieve results.

Disagree. It wasn't learned until the 80s that absent flush response can be due to PUFA deficieny.

3) Pyridoxine (Vitamin B6): 100mg to 200mg is given before meals and bed hour.

Agree for 100mg. Disagree for 200mg. Do not take more than 100mg B6 over the long term.

4) Cobalamin (Vitamin B12): 1000mcg. is given three times each week by needle

Partially agree. 1000mcg but daily, using sublingual methylcobalamin. Don't take B12 first thing in the morning. B12 follows a circadian rhythm and if your level is high in the morning it will keep you up at night.

5) Ascorbic Acid (Vitamin C): Ten to twenty grams should be taken daily by mouth in divided doses.

Agree for a short term course. Day to day, I take no more than 2g vit C per day.
http://www.mayoclinic.com/health/vitamin-c/AN01801

VITAMIN D3 There is no particular attention given to vitamin D3 in this protocol. MS patients generally need 4000IU per day but for safety, you need to carefully monitor the effects of your regimen on levels in your blood. ensure serum level of 25(OH)D3 is at least 100 nmol/L, preferably 125-150nmol/L

6) Riboflavin (Vitamin B2): 40mg to 80mg given daily by needle IM; 25 mg. before meals and bedtime.

Disagree. Just take 25mg (or more if that's how your pills are put together) before meals and at bedtime.

7) Vitamin E as d-alpha tocopherol acetate of d-alpha tocopherol acid succinate. 800 international units before meals and bedtime must be adhered to in this treatment.

Disagree. The state of knowledge on vitamin E has advanced significantly since this treatment was developed. Use an E8 complex. You can do the 800IU before meals etc in the short term, but 400IU E8 complex once a day should be enough in the long term.

8 ) Crude liver: daily injections of crude liver.

Disagree. No dosage specified, also see next point.

9) Adenosine-5-Monophosphoric acid

Disagree. No dosage specified. Mention of mysterious liver benefits and inosinic acid speak to me of uric acid. Uric acid links to MS were still in the future when this protocol was developed.

10) Choline: We give 700mg to 1400mg after each meal and at bed hour.

Undecided. I have not studied choline in detail. My choline is included in my B-complex, but the protocol says take Bs before meals, and choline after.

11) Lecithin: We give 1200 mg. Soybean Lecithin after each meal.

Agree. Personally I took this in the short term but it did not stay in my diet or supplement regimen long term.

12) Magnesium: 100mg. after each meal

Partially agree. Right now using my current brand, I take 150mg at a time. Some would advise taking before meals to take best advantage of stomach acid for absorption. Also K does not specify a form. I would suggest that magnesium glycinate or bisglycinate would be some of the best forms available now.

13) Calcium Gluconate (10 grain tablets): We give two tablets after each meal and at bed hour ... At times, this is given intravenously, one gram twice weekly.

Undecided. I take a calcium supplement (400mg twice a day, it's not gluconate either) to balance with my vitamin D magnesium and zinc intake.

14) Calcium pantothenate: We give 200 mg. after each meal and at bed hour.

Undecided. I have never researched or shopped for calcium pantothenate.

15) Aminoacetic acid (glycine): One heaping tablespoon of the powder in a glass of milk four times each day.

Disagree. Now that magnesium glycinate is available, you can get glycine that way.

16) Make certain that the hemoglobin is at least 13 grams.

Agree.

17) High protein diet with two to three eggs for breakfast.

Agree in the short term. I still have a breakfast like that a couple times a week, but the rest of the time it's usually mixed berries with yoghurt and a sprinkle of granola.

18) One Theragram-M cap. daily for trace minerals.

Partially agree. Any decent quality multivitamin and multimineral should be fine.

http://home.intekom.com/pharm/bm_squib/theragrn.html
Each THERAGRAN-M tablet supplies: Vitamin A 10 000 i.u.; Vitamin D 400 i.u.; Vitamin B1 10 mg; Vitamin B2 10 mg; Vitamin B6 5 mg; Vitamin B12 5 mcg; Niacinamide 100 mg; Calcium Pantothenate 20 mg; Vitamin C 200 mg; Vitamin E 15 i.u.; Iodine 0,15 mg; Iron 12 mg; Copper 2 mg; Manganese 1 mg; Magnesium 65 mg; Zinc 1,5 mg.

I had never followed up on this one until today, and this is the first I've realized that there is vitamin D in the Klenner protocol - not enough, but it's there at least.

19) Dantrium has value for relieving intentional tremor and Symmetrel for relieving stiffness in Multiple Sclerosis. Dose must be individualized.

Undecided. These are pharmaceutical drugs so I don't use them. However I have found magnesium to be effective against muscle stiffnes. Maybe the form of magnesium used, and/or the Klenner specification to take magnesium after meals, resulted in insufficient absorption to help with muscle stiffness.

20) Zinc gluconate: 10 mg. three times each day. Take several hours after vitamin B2.

Agree re dosage and form. My brand is zinc citrate and it works fine too. I have no opinion/idea about the timing.

anyway those are my thoughts on klenner. you can check out all the deets at the townsendletter klenner link below.
hope that helps!