CCSVI Syndrome by Team ZAMBONI - Key Papers
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
CCSVI Syndrome by Team ZAMBONI - Key Papers
MarkW
First - http://phleb.rsmjournals.com/cgi/reprint/25/6/269
Then - http://www.functionalneurology.it/commo ... 1ead753ee5
Next - http://www.ingentaconnect.com/content/m ... 8/art00006
========================================================
In this paper Prof Paolo Zamboni describes 'The CCSVI Syndrome'.
http://phleb.rsmjournals.com/cgi/reprint/25/6/269
I have started this as a new topic as there is much misleading information being quoted on CCSVI. If you post information which disagrees with this paper, be aware that I will challenge it if I spot it. My logic is simple - many people use this site for info on CCSVI and I want them to receive good info.
This paper is a clear statement of the syndrome found in pwMS and others. In academic environments a later paper on the same subject (CCSVI) replaces the authors' thinking as expressed in previous papers. P Zamboni and R Galeotti were the originators of the concept, so their definitions are the real ones. This is how medical science is developed.
For me this paper is absolutely crucial for everyone to read (using a medical dictionary as required).
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Answer to www.thisisms.com/ftopict-17537.html
Prof Z's paper answers your questions in the thread: http://www.thisisms.com/ftopict-17537.html.
Yes it is heavy to read but it is the full story.
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- thisisalex
- Family Elder
- Posts: 218
- Joined: Wed Dec 02, 2009 3:00 pm
- Location: Hungary
- Contact:
- CureOrBust
- Family Elder
- Posts: 3367
- Joined: Wed Jul 27, 2005 2:00 pm
- Location: Sydney, Australia
Re: CCSVI Syndrome - P Zamboni and R Galeotti
MarkW wrote:In this paper Prof Paolo Zamboni describes 'The CCSVI Syndrome'.
http://phleb.rsmjournals.com/cgi/reprint/25/6/269
I think I must of miss the paper, and it wasn't referenced, that proved CCSVI wasn't a syndrome caused by MS?P Zamboni and R Galeotti wrote:For instance the prevalence in MS ranges between 56% and 100%, indicating that CCSVI is one of the major risk factors for the development of MS.
PS be gentle, I have my third CCSVI treatment scheduled in the next two weeks, and it involves flying to the US for an IVUS


- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Use of English
I used this meaning of critical:
From Oxford English Dictionary - Critical =
"having a decisive or crucial importance in the success or failure of something: eg temperature is a critical factor in successful fruit storage"
I will try not to use non standard meanings in future.
I meant - This paper is crucial to understand Prof Zamboni's ideas.
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Syndrome or Cause
When you have less important things on your mind, have a look at the meaning of syndrome. Hint it is a collection of symptoms.
Also CCSVI is important in the development or progression of MS but this does not imply that it is a cause of MS.
Best wishes for your trip (to NY ?), mine (procedure 2) went well.
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Why no comments ?????
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
There is Dr. Zamboni's definition of CCSVI as a syndrome.Abstract
Chronic cerebrospinal venous insufficiency (CCSVI) is a syndrome characterized by stenosies
of the internal jugular and/or azygous veins (IJVs-AZ) with opening of collaterals and
insufficient drainage proved by reduced cerebral blood flow and increased mean transit
time in cerebral MRI perfusional study. The present review is aimed to give a
comprehensive overview of the actual status of the art of the diagnosis and treatment of
this condition. As far as the origin of venous narrowing is concerned, phlebographic
studies of the IJVs and AZ systems demonstrated that venous stenoses were likely to be
truncular venous malformations; mostly, they are intraluminal defects such as malformed
valve, septa webs. CCSVI condition has been found to be strongly associated with
multiple sclerosis (MS), a disabling neurodegenerative and demyelinating disease
considered autoimmune in nature. In several epidemiological observations performed at
different latitudes on patients with different genetic backgrounds, the prevalence of CCSVI
in MS ranges from 56% to 100%. To the contrary, by using venous MR and/or different
Doppler protocols, CCSVI was not detected with the same prevalence. Two pilot studies
demonstrated the safety and feasibility in Day Surgery of the endovascular treatment of
CCSVI by means of balloon angioplasty (PTA). It determines a significant reduction of
postoperative venous pressure. Restenosis rate was found out elevated in the IJVs, but
negligible in the AZ. However, PTA seems to positively influence clinical and QoL
parameters of the associated MS and warrants further randomized control trials.
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Key paper
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
A Syndrome is
- a group of signs and symptoms that occur together and characterize a particular abnormality or condition.
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
... "In several epidemiological observations performed at different latitudes on patients with different genetic backgrounds, the prevalence of CCSVI in MS ranges from 56% to 100%. To the contrary, by using venous MR and/or different Doppler protocols, CCSVI was not detected with the same prevalence."
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Lattitude and CCSVI Syndrome
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
CCSVI Syndrome is about stenosis and reduced flow
http://www.thisisms.com/forum/chronic-c ... 17842.html
It is an interesting intellectual debate but there is not sufficient data to be sure (in my rarely humble opinion).
Please just have your CCSVI symptoms diagnosed and treated.
MarkW
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
- MarkW
- Family Elder
- Posts: 1167
- Joined: Thu Oct 19, 2006 2:00 pm
- Location: Oxfordshire, England
- Contact:
Re: KEY INFO: CCSVI Syndrome - P Zamboni and R Galeotti
CCSVI Comments:
http://www.telegraph.co.uk/news/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
-
- Similar Topics
- Replies
- Views
- Last post
-
-
Lassman review for 2019. Top four MS papers.
by frodo » Mon Jan 20, 2020 12:51 am » in MS Etiology and Pathogenesis - 0 Replies
- 931 Views
-
Last post by frodo
Mon Jan 20, 2020 12:51 am
-
-
-
How to arrange to see Zamboni?
by violin » Sat Jul 20, 2019 11:25 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI) - 2 Replies
- 1953 Views
-
Last post by vesta
Tue Jul 30, 2019 1:28 am
-
-
- 2 Replies
- 1111 Views
-
Last post by Bobjones
Tue Feb 25, 2020 8:47 pm
-
- 0 Replies
- 442 Views
-
Last post by frodo
Thu Jun 04, 2020 12:39 am
-
-
Ccsvi still alive
by frodo » Tue Mar 17, 2020 2:22 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI) - 0 Replies
- 953 Views
-
Last post by frodo
Tue Mar 17, 2020 2:22 pm
-
-
-
Bosentan and chemical CCSVI
by frodo » Fri May 08, 2020 3:48 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI) - 1 Replies
- 425 Views
-
Last post by ThisIsMA
Tue Jun 16, 2020 9:25 am
-
-
- 0 Replies
- 256 Views
-
Last post by sin319
Fri Jun 05, 2020 8:59 am
-
-
Vegas CCSVI treatment healthcare providers
by sin319 » Fri Jun 05, 2020 2:39 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI) - 0 Replies
- 329 Views
-
Last post by sin319
Fri Jun 05, 2020 2:39 pm
-
-
-
CCSVI reloaded. Brave Dreams data re-analysed.
by frodo » Sun Nov 24, 2019 5:39 am » in General Discussion - 2 Replies
- 547 Views
-
Last post by frodo
Thu Dec 12, 2019 2:18 am
-