212 PML cases and 46 deaths in Tysabri MS patients

A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis
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MSUK
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212 PML cases and 46 deaths in Tysabri MS patients

Post by MSUK »

212 PML cases and 46 deaths in Tysabri MS patients as of March 1st 2012

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Biogen Idec have released the latest figures for PML cases and deaths following Tysabri infusions for Multiple Sclerosis

As of March 1, 2012, there have been 212 PML cases, of which 122 have been in the European Economic Area (EEA), 80 in the US and 10 in rest of world (ROW). 46 of the 212 patients with PML have died.

In 54 natalizumab-treated MS patients who developed PML and in whom serum samples were available 6-187 months prior to the onset of PML, all 54 patients had anti-JCV antibodies detected. ... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1905
MS-UK - http://www.ms-uk.org/
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Re: 212 PML cases and 46 deaths in Tysabri MS patients

Post by HarryZ »

The latest figures show that the number of PML cases last month skyrocketed from 212 to 232!!! Don't know if any more deaths have taken place.

This is the largest jump in monthly cases that I can remember.

http://chefarztfrau.de/?page_id=716
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Re: 212 PML cases and 46 deaths in Tysabri MS patients

Post by HarryZ »

squiffy2 wrote:212 PML cases and 46 deaths in Tysabri MS patients as of March 1st 2012

Image


Biogen Idec have released the latest figures for PML cases and deaths following Tysabri infusions for Multiple Sclerosis

As of March 1, 2012, there have been 212 PML cases, of which 122 have been in the European Economic Area (EEA), 80 in the US and 10 in rest of world (ROW). 46 of the 212 patients with PML have died.

In 54 natalizumab-treated MS patients who developed PML and in whom serum samples were available 6-187 months prior to the onset of PML, all 54 patients had anti-JCV antibodies detected. ... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1905
I notice that Biogen hasn't officially released the April 01 numbers showing an increase of the 20 additional cases of PML from March 01. I guess I wouldn't be in a hurry either to let customers know that info!
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Re: 212 PML cases and 46 deaths in Tysabri MS patients

Post by HarryZ »

Another 10 more cases of PML in the last month bringing the total to 242. Don't know if any more deaths involved.

http://chefarztfrau.de/?page_id=716
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