Synthetic protein targets EBV
Posted: Sun Nov 09, 2014 9:25 pm
UW researchers at the Institute of Protein Design have developed a synthetic protein called BINDI which binds to the Epstein-Barr Virus (EBV) protein BHRF1 responsible for immortalizing cells. Inhibition of BHRF1, a BCL2 homologue, may prove to be a useful treatment for EBV related cancers and other conditions stemming from EBV.
http://www.ipd.uw.edu/designer-proteins ... cer-cells/
http://www.cell.com/cell/abstract/S0092 ... %2900613-8
http://www.ipd.uw.edu/designer-proteins ... cer-cells/
http://www.cell.com/cell/abstract/S0092 ... %2900613-8