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My neuro is wanting me to start Plegridy soon. Anyone have experience with that? So far I've only tried Tecfidera but had to stop due to side effects.

Plegridy is easy to administer and for that I was willing to give it a try. I went into major depression and then extreme anxiety as a result...which is the first major side effect listed. For some reason Avonex did not affect me that way at all. I'd rather be off all meds that have this experience repeated. I wish you well in your journey no matter what you decide to take.