Cell-based study reveals vitamin D can drive ... myelin repa
Posted: Thu Apr 02, 2015 2:49 pm
Welcome to This is MS, the leading forum for Multiple Sclerosis research and support. Join our friendly community of patients, caregivers, and researchers celebrating over 20 years of delivering hope through knowledge.
https://www.thisisms.com/forum/
The authors found that neural stem cells carry receptors that can bind to vitamin D. When they added vitamin D to the cell culture plates, the neural stem cells increased their numbers significantly after one week, demonstrating that vitamin D triggers neural stem cells to activate and multiply. Importantly, vitamin D stimulated the neural stem cells to mature into both neurons and myelin-forming oligodendrocytes, but not astrocytes. The mechanism by which vitamin D activated neural stem cells was through promoting increased activity of several important neurotrophic factors.