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Immune system component found to be related to MS neurodegeneration

A study published in PLOS ONE provides new insights into the relationship between the immune system and neurodegeneration and clinical disability in MS, reports Multiple Sclerosis News Today.... Read More - http://www.ms-uk.org/immunecells

Any break in the blood brain barrier starts complement activation.
It's an inflammatory response, and not unique to MS.
This study found elevated levels of complement C3 in CSF.

We see the exact same response in ischemic stroke and acute brain injury.
http://www.smartscitech.com/index.php/I ... le/view/82

We also see this complement activation response in cardiovascular disease.
http://www.hindawi.com/journals/scienti ... 12/402783/

It's yet another connection to the vascular system in MS. The worse the hypoxic injury and breakdown of BBB, the more C3 in CSF, the worse MS disability and progression were.

Seriously...when are vascular researchers and neuroimmunologists going to start talking to each other?
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