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I have been on the protocol for one year now with no results. Perhaps it is because I have a genetic mutation VDR Taq. I am working with a local doctor and she suggests increasing my dosage. Will do. I have spoken to many people throughout the world but only one in North America. I hope this finally takes off with North American MS patients AND their doctors! I'm in a special care unit of a nursing home and I don't have much more energy!! I'm trying LDI Low-dose immunotherapy and have experienced increased strength in my leg muscles and reduced fatigue. Early days.
Bye, PN
Re: High Dosing vitD The Coimbra Protocol
Posted: Mon Nov 09, 2015 1:15 pm
by Scott1
Hi PN,
Sorry to hear you are in special care.
When you say low dose immunotherapy, what do you mean?
Regards,
Re: High Dosing vitD The Coimbra Protocol
Posted: Mon Nov 09, 2015 3:38 pm
by PointsNorth
Hi Scott, the worst part about the nursing home is the horrible food. I find that demoralizing. I've included an article on LDI which is taking low-dose allergy one step further to include autoimmune diseases.
I've been following closely a doctor in Alaska who I consider to be the godfather of LDI.
Re: High Dosing vitD The Coimbra Protocol
Posted: Mon Nov 09, 2015 4:20 pm
by ElliotB
Wishing you well...
Have you read The Wahls Protocol?
Have you added Biotin and/or any other supplements since you posted your protocol?
Re: High Dosing vitD The Coimbra Protocol
Posted: Mon Nov 09, 2015 11:01 pm
by PointsNorth
Thanks Elliot. I bought the Walls book sometime ago. Interested in her use of NMES equipment. Waiting to hear how people fair with Biotin round here.I will need my wife to make gelcaps for me. I spent 10 hours a day researching and corresponding with people across the globe!
Re: High Dosing vitD The Coimbra Protocol
Posted: Tue Nov 10, 2015 11:09 am
by ElliotB
The reason for my questions is that both The Wahls Diet/Protocol and Biotin are 'high energy' protocols and may help you feel a bit better.
Re: High Dosing vitD The Coimbra Protocol
Posted: Tue Nov 10, 2015 3:06 pm
by 1eye
PointsNorth wrote:Thanks Elliot. I bought the Walls book sometime ago. Interested in her use of NMES equipment. Waiting to hear how people fair with Biotin round here.I will need my wife to make gelcaps for me. I spent 10 hours a day researching and corresponding with people across the globe!
Doing pretty well. Coming up to 200 days. Not sure if I walk any faster, but I'm gaining a lot of core strength though sit-to-stand exercises.
Re: High Dosing vitD The Coimbra Protocol
Posted: Tue Dec 01, 2015 8:58 am
by vilnietis
PointsNorth, I'm sorry to hear high doses of vitamin D is not working for you so far. You are very unlucky. Most of patients are enjoying improvements every day, including me. Stay on protocol, I just read the other day that one male 51 years old started to walk again. He has MS for 15 years and was in wheelchair since 2014. After one year of waiting, he is able to use his legs again.
How did you found out about genetic mutation of VDR Taq?
Re: High Dosing vitD The Coimbra Protocol
Posted: Tue Dec 01, 2015 4:02 pm
by PointsNorth
Hi V,
Good to hear from you! I couldn't find out much more on VDR Taq as it relates to high dosing D. I have pushed my D consumption up to 115,000 IU per day. I am hoping that I see something by the end of next year. Fingers crossed.
V, how long did it take the guy in the wheelchair to see results? And do you know what level of D he was at?
Blood draw in another three weeks. I don't see that high dosing D upsets the balance too much. Everything of mine has stayed WNL within normal limits. Good to monitor though and stay on the safe side. We don't want hypercalcemia.
PN
Re: High Dosing vitD The Coimbra Protocol
Posted: Wed Dec 02, 2015 10:35 am
by vilnietis
Do you know your PTH value?
One patient was forced to take 160,000IU per day until his PTH dropped to lowest value. So the dose is really individual . I take 70,000IU and my PTH is now 8.0.
So I'm happy with that and I feel great, symptom free ;)
Re: High Dosing vitD The Coimbra Protocol
Posted: Wed Dec 02, 2015 12:26 pm
by PointsNorth
My last PTH is 1.3 nmol/L range is <7.
I will be inviting South Americans on the Coimbra protocol to this thread. They will need to translate Spanish and Portuguese into English! The reason why the vast majority of North American & European pwMS are not aware of what looks to be like a cure for MS and many autoimmune diseases!
NB you'll notice that I didn't call MS an autoimmune disease lest I offend certain individuals around here
Personally I believe that reflux causes blood to be placed on the brain courtesy of a weakened BBB. This is what I think triggers the immune response. Funny what you pick up from reading shit around here ). Please excuse my French.
Re: High Dosing vitD The Coimbra Protocol
Posted: Wed Dec 02, 2015 12:37 pm
by tzootsi
What I'm trying to determine is if the D protocol is to prevent relapses, or will it also help PPMS?
Super high dosing, like Coimbra, might not be necessary for everyone in order to get protective serum levels. In PN's case, he has a genetic defect on VDR. In southern CA, Jeff and I use more sun, less supplements, but we do have testing of our D3 levels every 6 months, to make sure all is good.
best,
cheer
Re: High Dosing vitD The Coimbra Protocol
Posted: Wed Dec 02, 2015 2:12 pm
by vilnietis
tzootsi,
Coimbra protocol works for all: RRMS, SPMS, PPMS. Vitamin D in high doses literally stops the progression. The high dose is determined during the first year. After disease activity becomes 0, that exact dose will be prescribed for a rest of your life. Usually doctors want to follow patient for two years to determine the correct dose ;)