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Can brain cell death trigger multiple sclerosis?
Posted: Fri Feb 12, 2016 3:56 am
by MSUK
One trigger for multiple sclerosis (MS) might the death of brain cells that make myelin, according to a study published in the journal Nature Neuroscience...Read more -
http://www.ms-uk.org/MSnews
Re: Can brain cell death trigger multiple sclerosis?
Posted: Fri Feb 12, 2016 7:02 pm
by CureOrBust
http://onlinelibrary.wiley.com/doi/10.1 ... 6/abstract
Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
Michael H. Barnett MBBS andJohn W. Prineas MBBS*
Article first published online: 23 FEB 2004
...extensive oligodendrocyte apoptosis and microglial activation in myelinated tissue containing few or no lymphocytes or myelin phagocytes...
And also discussed here on TIMS
http://www.thisisms.com/forum/general-d ... html#p2408
Re: Can brain cell death trigger multiple sclerosis?
Posted: Tue Feb 16, 2016 1:09 am
by Leonard
MSUK wrote:One trigger for multiple sclerosis (MS) might the death of brain cells that make myelin, according to a study published in the journal Nature Neuroscience...Read more -
http://www.ms-uk.org/MSnews
Quote from the article under the link:
The researchers believe that oligodendrocyte death can be caused by a variety of factors, including developmental abnormalities, viruses, bacterial toxins, or environmental pollutants. For human patients, it may not be until years after an initial injury that the brain triggers oligodendrocyte death, the study authors hypothesise.
Of course, they hit the main issue. And it is not an 'or', it is an 'and'.
For a further explanation, see the Thesis MS Unravelled on
http://www.thisisms.com/forum/general-d ... 27300.html