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Low Nfl's (Nurofilament levels) in Lumbar Puncture results

Posted: Sat Jun 24, 2017 3:09 am
by Luvsadonut
I had another spinal tap done recently and my nuero pointed out that my Nfl levels are lower than the average Joe. When I was diagnosed 18 years ago I didnt have a ST so this is the first time Ive come across Nfl's. My spinal lesions were still in abundance but Id like to know a little more about these Nfl's. Does anybody know how the Nfl levels play a part in the disease progression? Do they indicate inflammation? Are they a marker of any sort? Done some googling but difficult to decipher..

Thanks

Re: Low Nfl's (Nurofilament levels) in Lumbar Puncture resul

Posted: Sun Jun 25, 2017 1:30 am
by NHE
I seem to recall that Nfl in CSF is supposed to be a biomarker for axonal damage.

http://www.thisisms.com/forum/general-d ... ml#p246642

http://www.ms-uk.org/blood-testing-leve ... ise-280916