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Association of Developmental Venous Anomalies with Demyelinating Lesions in Patients with MS

Source: https://www.ncbi.nlm.nih.gov/pubmed/28912286

Abstract

We present 5 cases of demyelination in patients diagnosed with multiple sclerosis that are closely associated with a developmental venous anomaly.

Although the presence of a central vein is a known phenomenon with multiple sclerosis plaques, demyelination occurring around developmental venous anomalies is an underreported phenomenon.

Tumefactive demyelination can cause a diagnostic dilemma because of its overlapping imaging findings with central nervous system neoplasm.

The relationship of a tumefactive plaque with a central vein can be diagnostically useful, and we suggest that if such a lesion is closely associated with a developmental venous anomaly, an inflammatory or demyelinating etiology should be a leading consideration.

How CCSVI can be the direct cause of demyelination. I think Dr. Zamboni and the other doctors originally called CCSVI a developmental anomaly. Now we see how it directly causes MS, when the problem is colocated with a central vein. This comes from an underreported phenomenon, demyelination occurring around developmental venous anomalies. In other words, CCSVI. Can we start reporting it as such? I promise, it won't hurt a bit.