excellent info thx. a trial of up to 400 mg mag glycinate per day could be worthwhile (but again, best to emphasize mag rich foods first and foremost).
if you had not had a chance to click through re the highly relevant 2b below, here it is again:
http://www.thisisms.com/forum/general-d ... ml#p250969
also (not sure why mag glycinate was not selected for this comparison)
Study of magnesium bioavailability from ten organic and inorganic Mg salts in Mg-depleted rats using a stable isotope approach (2005)
http://bit.ly/2kEK9s0
"Eighty male Wistar rats ... received, for two more weeks, the same diet repleted with Mg ... as: oxide, chloride, sulphate, carbonate, acetate, pidolate, citrate, gluconate, lactate or aspartate ... Organic Mg salts were slightly more available than inorganic Mg salts.
Mg gluconate exhibited the highest Mg bioavailability of the ten Mg salts studied."
why no mag glycinate? TBD.
related:
Speciation studies in relation to magnesium bioavailability. Formation of Mg(II) complexes with glutamate, aspartate, glycinate, lactate, pyroglutamate, pyridoxine and citrate, and appraisal of their potential significance towards magnesium gastrointestinal absorption (1987)
http://www.sciencedirect.com/science/ar ... 9300812967
"At usual therapeutic concentrations, pyroglutamate and pyridoxine do not coordinate magnesium in appreciable amounts, and
glycinate and lactate do not form any neutral complex*. In contrast,
glutamate, aspartate and citrate do form neutral magnesium species**; the extent of their expected effects with respect to magnesium uptake by enterocyte membranes is discussed on the basis of relevant computer simulations."
related questions:
* good thing bc these non neutral forms will want to interact?
** sounds less useful - good thing, bad thing or just one necessary piece of the overall puzzle?
@NHE this ^ looks like your alley, yes no maybe so?
now having sifted through the lit for studies examining magnesium glycinate in particular, i am quite surprised to note a distinct dearth of research attention. did find this however:
Magnesium Glycinate Supplementation in Bariatric Surgery Patients and Physically Fit Young Adults (2013)
http://www.fasebj.org/content/27/1_Supp ... b291.short
"... results obtained in this pilot work suggests that young fit adults, as well as people who have had bariatric surgery, tend to have less than optimal magnesium intake. The glycinate form of magnesium can improve magnesium status. In addition, in the pilot work, no reports were given of diarrhea, which can be a problem with some types of magnesium supplements."
ok great - now can we get a comparison to gluconate's bioavailability... (to date, short answer appears to be no)
so, from the above, looks like one of three of your product's components will be working for you most effectively.
question: does your label give a breakdown in terms of mgs per pill for each of oxide, gluconate and lactate?
whether it does or no, may well be a good idea to trial mag glycinate. the drain on your body's mag resources resulting from stress is nothing to take lightly!