Anti-MOG?
Posted: Tue Apr 17, 2018 2:09 pm
Hi All,
My quick history:
2010: optic neuritis right eye, confirmed on orbit MRI but with negative brain and spine MRIs. Four months to 20/15 from 20/40 but it took over two years to regain full color and contrast. Still see snow to this day, but hardly notice.
2015: Fatigue and strange exertion related symptoms following a one day splitting headache and mild fever. Also had my first opthalmic migraine in this post fever period, and continue to have them once every three months or so. A check up found I was seronegative for NMO-IgG, with negative brain and spine MRIs. Exercise still leaves me feeling weirdly fatigued most times, even when in shape.
2018 (last week): optic neuritis left eye, also confirmed on orbit MRI but with negative brain MRI. I'm 20/100 this time around. Spine MRI and LP next week. Blood anti-MOG results are pending, to repeat with CSF and in conjunction with MS panel. Also seronegative for NMO-IgG.
My doctors are leaning toward anti-MOG autoimmunity versus MS or NMO.
Has anyone experienced similar?
My quick history:
2010: optic neuritis right eye, confirmed on orbit MRI but with negative brain and spine MRIs. Four months to 20/15 from 20/40 but it took over two years to regain full color and contrast. Still see snow to this day, but hardly notice.
2015: Fatigue and strange exertion related symptoms following a one day splitting headache and mild fever. Also had my first opthalmic migraine in this post fever period, and continue to have them once every three months or so. A check up found I was seronegative for NMO-IgG, with negative brain and spine MRIs. Exercise still leaves me feeling weirdly fatigued most times, even when in shape.
2018 (last week): optic neuritis left eye, also confirmed on orbit MRI but with negative brain MRI. I'm 20/100 this time around. Spine MRI and LP next week. Blood anti-MOG results are pending, to repeat with CSF and in conjunction with MS panel. Also seronegative for NMO-IgG.
My doctors are leaning toward anti-MOG autoimmunity versus MS or NMO.
Has anyone experienced similar?