hi again
i am so sorry to read about your first DH. i can't imagine :S
re the important other details posted, let's address this rather large red flag:
- "Last VitD was 43.7 ng/mL ; In recent years I have struggled with maintaining my VitD level and take a 10,000 unit chewable each day, as my PCP felt I had an absorption issue with the pills because my levels never came up. Lowest result was 15.5 ng/mL".
so with ms as a possibility, you could likely aim for serum 25(OH)vitD3 50-60 ng/ml
as long as you are paying attention to other important supporting nutrients.
recalcitrant low d3 status (ie the poor response to pils) screams cofactor issues, ie specific low or absent essential nutrient cofactors needed to interact with d3 for optimal absorption and utilization.
10,000iu of d3 per day without mineral balancing, esp magnesium, may be linked to several of your symptoms.
high dose d3 will be pulling magnesium from your fluids and tissue if it doesn't get enough to work with from a combined dietary and supplemental intake.
so with that said, three questions:
1. could you share your daily routine where multivitamins, multiminerals, or specific mineral supplement products are concerned?
2. how many mgs of magnesium do you estimate you are getting daily from diet and supplements combined?
3. if mineral supplements are in the mix, which specifically do you use, and how have you been timing them in relation to that d3 chewable?
as a previous victim of magnesium deficiency secondary to excessive vit d3 intake, i look forward to your reply
going forward, if your PCP is on board with doing a couple more tests, it could be wise to
ensure high normal status for both serum magnesium and serum zinc.
related reading of possible interest:
viewtopic.php?f=27&t=30924
as an fyi, gluten increases essential nutrient demand. a gluten free diet is one way to help deal with a nutrient poor diet. mind you, it's not the *only* way. another less restrictive option is to boost overall essential nutrient intake via increasing nutrient dense foods, and avoiding
excessive gluten. i used to react poorly to gluten (eg discomfort and bloating), especially when zinc deficient. since correcting my zinc deficiency and working on overall nutrient status and *limiting* gluten intake, no lingering issues (that is not to say i haven't done some permanent damage with other nutrient deficits, but at least the gluten sensitivity is over). my cognitive improvements after boosting zinc were dramatic.
related:
Serum zinc in small children with coeliac disease (2009)
https://onlinelibrary.wiley.com/doi/abs ... 08.01085.x
"...
Serum zinc concentration is decreased in untreated coeliac children with enteropathy and
normalizes on gluten‐free diet."
Correlation Between Dietary Zinc Intakes and Its Serum Levels with Depression Scales in Young Female Students (2010)
https://link.springer.com/article/10.10 ... 009-8572-x
The main objective of this study was to assess the correlation between serum zinc concentrations and dietary zinc intakes with depression scores ...
dietary zinc intake is correlated to its serum concentrations; however, the serum zinc levels are inversely correlated to depression scales.