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TNF demyelination considered as MS

Posted: Wed Feb 24, 2021 2:05 am
by frodo
TNF-α blockers-associated multiple sclerosis

https://www.sciencedirect.com/science/a ... zPB3em-Fdg

Conclusion

Our study confirmed that the exposure to TNFα blockers can be associated to a broad spectrum of CNS demyelinating disorders.

In our cohort, TNFα blockers-associated Multiple Sclerosis does not seem to be associated with a more aggressive course and can be managed with MS-specific DMTs, chosen considering the clinical course and the concomitant autoimmune disease.

Our findings need confirmation in larger cohorts to further characterize the disease course of TNFα blockers-associated Multiple Sclerosis.