This Is MS Multiple Sclerosis Knowledge & Support Community

My wife and I got the 2nd dose of the Moderna vaccine for Covic19 yesterday. I'm having soreness in the shoulder at the injection site. That was minor. But today I'm feeling very weak. This is much worse than the 1st shot. It was a struggle getting out of bed. Just for the record I have the PPMS variety of MS. It started about 25 years ago.

My wife had very little trouble with either shot.

Wife and I also had both Modernas. My wife has PPMS - first shot was fine, 2nd shot gave her flu like symptoms for about 30 hours - fatigue, achy joints, slight nausea. I had slight chills on 2nd dose. We are both fine now.