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Remyelination stops degeneration in MS

Posted: Fri Mar 04, 2022 2:12 am
by frodo
Probably this also means that degeneration is a direct consecuence of demyelination. This was not clear before this report.

Remyelination stops degeneration in MS

https://www.nature.com/articles/s41582-022-00638-5

Findings that remyelination protects axons from degeneration in animal models of multiple sclerosis (MS) have been replicated in humans in a study published in the European Journal of Neurology.

PET and MRI were used to monitor demyelination and remyelination in white matter lesions in 19 people with MS over a 4-month period.

A higher index of remyelination was associated with greater preservation of the microstructure of surrounding tissue, indicating reduced neuroaxonal damage.