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2023 Aug 10
Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA
Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication
https://pubmed.ncbi.nlm.nih.gov/37664626/

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2015 Jun 4 Rashida Ginwala , Emily McTish Department of Microbiology and Immunology, and the Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia

Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions
https://pubmed.ncbi.nlm.nih.gov/26040501/

https://scholar.google.gr/scholar?hl=el ... osis&btnG=

Bear in mind it's poor bioavailability so choose a liposomal form

The following paper discusses the polyphenol content of various herbs and other dietary sources common in the Mediterranean diet. This includes apigenin. Many sites list chamomile as being a rich source. However, celery seed is considerably greater. The values are 3-5 mg/100 g for chamomile and 78.65 mg/100 g for celery seed. I used to use celery seed in my cooking. I found it to have a strong flavor which was easily overdone. A better option may be to encapsulate the celery seed.

Polyphenols in the Mediterranean Diet: From Dietary Sources to microRNA Modulation
Antioxidants (Basel). 2021 Feb 23;10(2):328.

It is now well established that polyphenols are a class of natural substance that offers numerous health benefits; they are present in all plants in very different quantities and types. On the other hand, their bioavailability, and efficacy is are not always well proven. Therefore, this work aims to discuss some types of polyphenols belonging to Mediterranean foods. We chose six polyphenols—(1) Naringenin, (2) Apigenin, (3) Kaempferol, (4) Hesperidin, (5) Ellagic Acid and (6) Oleuropein—present in Mediterranean foods, describing dietary source and their chemistry, as well as their pharmacokinetic profile and their use as nutraceuticals/supplements, in addition to the relevant element of their capability in modulating microRNAs expression profile.

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