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Some research on ALA / MS use doses such as 1200mg. I checked the fine print on mine and it's..100mg.

I'm curious what others are taking? NHE encouraged me to look into ALAs impact on brain atrophy...

CAGirl wrote: ↑Thu Aug 01, 2024 7:56 pm Some research on ALA / MS use doses such as 1200mg. I checked the fine print on mine and it's..100mg.

I'm curious what others are taking? NHE encouraged me to look into ALAs impact on brain atrophy...

I take 200 mg/g of Na-R-Lipoate. It's absorbed roughly 3x better than R-Lipoic Acid so the equivalent dose is 600 mg/day. This is the same dose used in research by Dennis Bourdette at Oregon Health Science University.

https://www.medicalnewstoday.com/articles/318225

However, Dennis Bourdette's research utilized Alpha Lipoic Acid which is a 50/50 mix of the R and S forms. The S form of Lipoic Acid has a physiological cost to it and is less effective than the R form. Please see the following post for a discussion of the differences between the R and S forms.

viewtopic.php?p=29715#p29715

CAGirl wrote: ↑Thu Aug 01, 2024 7:56 pm Some research on ALA / MS use doses such as 1200mg. I checked the fine print on mine and it's..100mg.

I'm curious what others are taking? NHE encouraged me to look into ALAs impact on brain atrophy...

I give to my wife 2x240mg Na-R-Lipoate from Life Extention.
If NHE is right it is equivalent to more than 1200mg researchers use.

NHE and DJM thanks for your response. I'll aim for 200 of R-Alpha-Lipoic Acid (twice what's on the bottle as the recommended dose). May I ask both of you while this supplement is a strong antioxidant is there a super supplement to target inflammation? I maintain a low-inflammation diet + exercise + lots of sleep but want to do more.

Hi CAGirl,

CAGirl wrote: ↑Wed Aug 07, 2024 1:26 pm May I ask both of you while this supplement is a strong antioxidant is there a super supplement to target inflammation? I maintain a low-inflammation diet + exercise + lots of sleep but want to do more.

Curcumin functions as an anti-inflammatory. I would recommend an absorption enhanced formulation as plain curcumin is nearly useless. It's modified by the liver and very little is absorbed. I take Longvida Curcumin. However, CurQfen Curcumin would also be a good choice.