Possitve MRTC

Lars · Post by **Lars** » Sat Apr 07, 2007 11:06 am

Hi all,
Found out today that my mrtc was possitive. Apparently the Advair steriod in question made little or no difference. Maybe the bar has indeed been lowered. I have stopped Advair and swithed to Singular which seems to be working so far. I will schedule bag o' blood Monday.

sh8un · Post by **sh8un** » Sat Apr 07, 2007 2:42 pm

Yeayyyyyyy!

Loobie · Post by **Loobie** » Sat Apr 07, 2007 3:19 pm

Good to hear Lars.

Lars · Post by **Lars** » Sat Apr 07, 2007 5:27 pm

I am a bit curious if anyone knows how the mrtc test works? Is is a straight pass/fail. A certain percentage or number that is required? Cells per million or some such scale? Because like everyone else I wonder why, if all msers have mrtc's why are there any neg. tests.
Thanks,
Lars

Lyon · Post by **Lyon** » Sat Apr 07, 2007 9:36 pm

First off, CONGRATULATIONS!

Second, Tim is in the process of reworking his webpage and adding a bunch more FAQ's but for now read through this page http://www.msu.edu/~lyonro/tovaxinhst.html

The webpage is something I slapped together pretty quickly, but if I remember correctly, the questions I asked Tim were just about the same ones you're asking.

If I understand correctly, everyone produces mrtc's, not just people with MS. The difference is that for some reason the systems of people with MS don't keep the mrtc's under control.

Because everyone produces mrtc's, everyone with MS produces mrtc's. From what I gather, Opexa is able to isolate the mrtc's from everyone who attempts to get into the clinical trial.

It seems a bit of incorrect terminology has been involved by us laypeople when we've talked about mrtc's being detected because mrtc's are detected in everyone. The problem (evidently) arises because with some people so few mrtc's are able to be isolated, or their mrtc's multiply so slowly, that the vaccine can't be created in the necessary time period.

It's conjecture on my part but I suppose a possible future option for those who have been turned down for the Tovaxin trial would be dosing at whatever rate Opexa can produce the vaccine for them....once or twice per year?

Bob

TWG · Post by **TWG** » Wed May 07, 2008 9:48 am

Lars, I was under the impression from the staff there that I was one visit ahead of you, and this Friday is the last visit for my phase IIb were they will check for MRTC's and then schedule the big bag 'O blood draw. What am I missing? But congratulations!

flipflopper · Post by **flipflopper** » Wed May 07, 2008 12:23 pm

That's great Lars!

I went for my last appointment of the phase IIb trial last Monday. I should know in about 2 weeks if they can make a vaccine for me or if I will have to be retested in 3-4 months.

ssmme · Post by **ssmme** » Wed May 07, 2008 1:04 pm

If you don't hear back when you think it's time make sure you call Shannon at Opexa. She seems to respond quickly even if you don't get a direct call from her it seems that things happen quickly after she's aware.

Lars · Post by **Lars** » Wed May 07, 2008 3:36 pm

Wait, wait, wait. I'm not sure how this thread has resurfaced, it is from April 2007, my 11b MRTC results. I appreciate the good will but I am a month and a half from my extension test. Just out the door for my 2nd to last visit, I'm late to pick up my wife, ouch.
Thanks,
Lars

flipflopper · Post by **flipflopper** » Wed May 07, 2008 9:33 pm

This thread was on the top of the Tovaxin section when I visited the site, I read very quickly and I didn't notice the date

ssmme wrote:If you don't hear back when you think it's time make sure you call Shannon at Opexa. She seems to respond quickly even if you don't get a direct call from her it seems that things happen quickly after she's aware.

That is what I will do if it takes much longer than 2 weeks to hear back. It is so useful to look at this site and read the experiences of all those who are ahead of me in this trial