I've started on doxcycline after contacting David Wheldon.
1998 i was admitted to hospital with retrobulbar neuritis and spastic weakness.I was told they thought I had MS, however MRI scans were normal.I was discharged from first Neuro going from MS to ME.
I got a second opinion with an MS Specialist who said he thought it was MS but rare not to show lesions.I do show optic atrophy on MRI.As early as 2000 I noticed I felt better after taking certain antibiotics,less fatigue could walk further and I could think straight.I even said to one Neuro in 2001 I would like to try minocycline if it came on trial in the UK as I always felt I had an infection.
My symptoms increased with severe spasms and spasticity,taking high doses of Baclofen and diazepam,some days could hardly walk around the house.I was given a brace crutches and use a wheelchair outdoors.
Ms Specialist was talking about aggressive therapy,but once again my brain MRI came back normal.Anyway he discharged me in August saying they just haven't identified whatever it is yet.He did suggest to my GP trying 3 to 6 months antibiotics for prolonged benefit.
As I have permanant visual loss in left eye,weakness and spasticity,my right foot had contracted inwards with spasms and my mobility deterioated so much I decided with my GP I just couldn't carry on without trying antibiotics.
It's something I have noticed for a while and seems to help my stiffness and spasms
My Gp told me to stop the doxycycline as he had to put me on a 10 day course of amoxycillin.I've now started again on the doxycyline again and keeping my fingers crossed that I will benefit from it.