Google some photos of the lyme borreliosis rash, erythema migrans, to see if that looks like the rash he had. The typical rash is somewhat variable, but not terribly similar to any other rash. Read multiple sources if you want to get all the details. Please note that the rash fails to occur
in 50% or more of lyme borreliosis cases.
The answer to your question is yes, there are doctors who would very likely diagnose your husband with lyme borreliosis based on a positive IGeneX serology and MS symptoms. They are members of the professional organization ILADS. Other doctors, including most MS neurologists, would disagree entirely, but personally I find they strongly overstate the power and completeness of their arguments. They may also criticise IGeneX, which I dont think has published any work investigating the value of their testing.
The links between lyme borrelia and MS are these:
- demyelination has been observed in a percentage of cases dx'd as neurologic lyme borreliosis (the dxs may be arguable; as you probably know MS is a "soft" dx with very debatable bounds, and some might say these patients have MS)
- in a controlled pilot investigation, Brorson et al directly detected spirochetes in the cerebrospinal fluid of 10 MS patients. Full text of this paper is on google; email me if you want to also see the pcitures.
- theres a few other odd links
IMO, the meaning of borrelia in chronic illness is unclear. Clearly, there are many who had definite acute lyme disease (the erythema migrans rash is distinctive) whose health was permanantly ruined, and who respond very well (but often very slowly) to antibacterials. Quite the strongest likelihood IMO is that these people have a chronic, refractory, virulent lyme borrelia infection.
However, I am not satisfied that a high lyme serology means lyme is ones sole/primary infection. After all, ill health might
allow a harmless, small persistant borrelia infection to multiply limitedly, causing the serology to become positive. However, I am familiar with the history of antibacterial treatment in quite a few MS patients and patients with other poorly-understood diseases of immune activation. Results are rather favorable on average, with much variation. IMO, it is very difficult, and not overwhelmingly important, to discern with much confidence the identity of any bacteria that may be involved in ones disease. However, diagnosis is a practical art, and the fact that many ILADS member doctors would be likely to treat for lyme in your husbands case may be of practical use.
If I havent completely bored you yet, you might read my post at the bottom of this page for more details: http://tinyurl.com/8hvf2
Risks should be studied and understood by anyone contemplating a non-standard treatment.
I dont have MS, I have CFS. Please note, I study disease and microbes, and may enter grad school next year in this capacity, but I am currently a college undergraduate with no qualifications whatsoever.