MS Interferon Drugs -- Brain Atrophy and Other Problems

A board to discuss the Multiple Sclerosis modifying drug Betaseron

Will these studies cause you to reconsider taking an interferon?

Yes, I will not take an interferon.
2
40%
No, I am not frightened by the studies.
2
40%
Unsure. I need more information.
1
20%
 
Total votes : 5

MS Interferon Drugs -- Brain Atrophy and Other Problems

Postby Rebecca » Sat Mar 06, 2010 11:41 pm

There are two very important studies of which everyone needs to be aware. The first shows that the use of interferons such as Betaseron results in gray matter atrophy (brain shrinkage). Here is a link:

<shortened url>

The second study shows that when the interferons cause the development of antibodies, these antibodies cause a worsening of MS symptoms -- even long after taking the medicine is stopped. Here's a link to that study:

http://www.takingcontrolofmultiplescler ... BS_108.pdf

This stuff is shocking and we need to make sure everyone is aware of these problems.
User avatar
Rebecca
Family Member
 
Posts: 30
Joined: Mon Nov 30, 2009 4:00 pm

Advertisement

Postby justjazz » Mon Mar 08, 2010 12:22 am

deleted
Last edited by justjazz on Thu Mar 11, 2010 11:08 pm, edited 1 time in total.
User avatar
justjazz
Getting to Know You...
 
Posts: 11
Joined: Sun Mar 07, 2010 4:00 pm

Re: MS Interferon Drugs -- Brain Atrophy and Other Problems

Postby NHE » Mon Mar 08, 2010 3:20 am

Hi Rebecca,
That's an interesting paper that you have referenced. I will certainly have to obtain the full article. In addition to the other study mentioned above, you may wish to review the third figure in the following post and also read the linked abstract. http://www.thisisms.com/ftopicp-60622.html#60622

Avonex has been shown to decrease brain atrophy during the second year of treatment vs placebo.


I'm not trying to persuade anyone that Avonex is great, I'm merely noting that there has been conflicting evidence published in the past.

NHE
User avatar
NHE
Volunteer Moderator
 
Posts: 3355
Joined: Sat Nov 20, 2004 4:00 pm

Re: MS Interferon Drugs -- Brain Atrophy and Other Problems

Postby MrsMomTo6 » Tue May 28, 2013 10:01 pm

What is the MOST discouraging about this is:

1-I never knew it, or found such research when I said 'yes' to taking betaseron.
2-No Neuro reads the MRI reports the same...so, I feel like I never really know the full extent of my MRI reports.
3-I KNOW I have had more issues in the year since I stopped Betaseron, but, I had a pitiful reading of my MRI that basically said, 'findings concurrent with a demylenating process like MS' REALLY!?!?! a brain MRI on an 'MS PATIENT" whose MRI reveals MS?!?! shocking revelation!!!

Even when I had my neuro RE-read it, he did not even discuss all the areas where issues were found, just a brief explanation of what he saw...unlike my 'old' Neuro, who spoke on and addressed EVERY single abnormal thing he saw on the MRI...but, he was the one who prescribed Betaseron...
MrsMomTo6
Getting to Know You...
 
Posts: 17
Joined: Tue May 21, 2013 9:40 pm


Return to Betaseron

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: No registered users


Contact us | Terms of Service