Personally I'm doing very well. I've had no relapses since my initial dose in October of 2003. When I signed up for the study the neurologist who was doing the observations for the study rated my disability at 2.5 on the EDSS scale.
I dropped to a 1.5 EDSS score after 9 months, and I have a feeling that I've dropped lower than that since then. At my last check up the neuro who tested me ( we have to go in for quarterly check ups as part of the study) wasn't the usual one as he was at the hospital with a patient (no one on the study), but this guy didn't know that I was on Campath as the neuro is supposed to be "blinded" as to what group I'm in on the study. Guess I'll have to wait until April for my next appt. to find out.
However, at this point I feel great and I'm quite happy to keep leaving my handicapped parking hang tag unused and collecting dust in the kitchen drawer
The only "official" disability I have left is called "hyper reflexes" which really isn't that much of a problem other than I look kind of odd when trying to walk down stairs. Actually it's kind of cool..... having Hyper Reflexes makes it sound like I have super powers
But as for as day to day living, no one would guess that there is anything wrong with me, quite different from a year or so back when I would draw strange looks from people when walking (stumbling? shuffling?) through the grocery store or having co-workers quietly question my wife about what was up with me.... many thought I'd gotten hurt somehow.
Needless to say, I'm quite happy with the results thus far.