Checking for Dr. Zagon's studies I found the followingSammyJo wrote:[...] "The next message I want to get out there is that LDN is a logical therapy adjunct for CCSVI. The papers Dr Zagon has written on the angiogenesis effects of LDN have many connections that need to be explored in the context of MS as a
This clearly means that taking LDN should increase the production of OGF. But this should lead to the inhibition of angiogenesis.In his early studies of opiate antagonists on cell growth, Zagon discovered that low doses of opiate antagonists such as naloxone and naltrexone blocked opiate receptors for approximately four to six hours. This resulted in increased production of endogenous opiates once the blockade ended. In subsequent studies Zagon determined that the primary importance of this blockade is the increased production of opioid growth factor (OGF).
Zagon and his team have also determined, in animal studies using chick eggs, that opioid growth factor has a significant inhibitory effect on angiogenesis. Their studies showed that both the number of blood vessels and the blood vessel length were decreased in vivo.
There's no way in hell I can follow that much miscellaneous info on a single, long thread. I'm particularly interested in US media, but work full time. I can't slog through these newly formed, gigantic, conglomerate threads to find the posts I meant to reply to when I had time.
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