As regards the valve issue, would be interested Dr Sclafani if in case of several CCSVI issues found in a patient in different places (eg two or three), were these always of the same type? For example, all with problems of pathologic valves or all due to stenosis of the wall... I have only been wondering since CCSVI is congenital then maybe one has maybe genetically the same type of pathology in several veins in the body?
The body and its pathology is rarely that boring. In the case of CCSVI, there are so many variations of the disease and its anatomical pathology
To date I have seen the following: In most patients they are mixed
1. Anomalous confluens of jugular vein
2. Absent Jugular vein
3. annular stenoses
4. hypoplasia, isolated
5. hypoplasia, multiple tandem
6. duplications with stenosis
7. reversed valve
8. incomplete or fused valve leaflets
9. misplaced valve
10. false channels (may be incomplete jugular duplication)
13. abnormal drainage of external and vertebral veins
So variation is the rule.
And an additional question: if in the azygous those valve issues are often not detected or underestimated...hmmm...with a friend of mine that also has extensive spinal cord issues no stenosis in the azygous was found, but he got angioplasty of his left internal jugular, where a larger stenosis was found.
(I still wonder that it is indeed "enigmatic" not to detect these valve problematics in the azygous after MRV and then the catether venography at the moment of percutaneous venoplasty itself?! Are they easier to detect in the jugulars since there the doppler exam reveals them? So in the MRV you would not see a malformed valve in the jugular that you saw in the doppler exam? And what could be done to improve techniques to find these valve pathologies in the azygous?)
people will see what they are prepared to see. When I finally get back in the saddle, i promise that all these findings, and more, i assume, will need to be publishes and explained so that those who want to treat in the future, do not have to figure it out from scratch.
My friend had some improvements with sight (black curtains gone) and more energy/less fatigue...but as regards the potential preventative effect that might relate to CCSVI and then the prevention of further spinal myelin damage we are now wondering...if the azygous really not affected, maybe one of these other venous passages ?? Guess for the moment only god knows...[/quote]