This Is MS Multiple Sclerosis Community: Knowledge & Support

Thanks for the info, and while I still hope he responds, the info you gave me will/is be most helpful!

Dear Dr Scaflani,

I live in Australia and here they can only do extracranial doppler US.

My question is, if a venogram is done will it pick up any stenosis in the transcranial area? In other words, will the venogram pick up any stenosis from top to bottom of the jugualr veins?

Sorry for my ignorance.

Kind regards

Interesting that you note chemical trauma. I have always had very, very slow progression. In fact I was able to remain in the closet about MS for almost 20 years. Then I participated in a trial for treatment of MS by infusion of mitoxantrOne. It did me no good, had horrible side effects and soon after my last infusion I had a visible collapse of a vein on the surface of my arm. My rate of progression has since accelerated, although I understand it usually slows down after age 50. Also the phlebotomists have a terribel time finding a good enough vein for blood draws.

Could systemic vein injury contribute to worsening CCSVI?

Some insurers do pay for ccsvi

His position as an advisor goves him a loud voice
My dealings with him have been collegial. It is not my intention to disparage him but to convince him

Good luck in your treatment. I wish u some freedom on independence day.
I hope u don't need stents. I think it best to have successful venoplasty without stenting. However I have had an opportunity to learn that short term deliterious effects of stents are low. Now I will have to learn the long term deleterious effects before I become more liberal in the use. My tratment plan calls for stenting after second short term recurrence

Antocoagulation os used to avoid stent thrombosos and restenosis

Good day, Happy 4th! and thank you!

my question(s).. chicken or egg kind of.. hypothetically afflicted from birth.. is a malformed valve the cause of a vein stenosing? causing a reduced flow/reflux that causes the vein to become insufficient? and if so.. are the valves being repaired somehow during the procedure? most talk is of vein ballooning.. how does this address the valve?

not that you need more to read.. http://healthblog.ctv.ca/post/CCSVI-tri ... stion.aspx

I thought i answered this question, but cannot find the answer wo i will answer it again

firstly,
apologize only for ignorance you choose not to correct.

The usual catheter venogram does not visualize the intracranial veins. However the catheter venogram will pick up stenoses from the top to the bottom of the jugular vein, which actually begins in the neck, not in the skull or brain. The veins that are inside the skull are deep cerebral veins and dural sinuses which are the outflow pipes inside the skull. They drain into the jugular veins and vertebral veins, once they exit the skull.

MR venograms do show the dural sinuses and the deep cerebral veins are visualized on susceptibility weighted MRI

The ultrasound only visualizes the jugular and vertebral veins but not with as great detail as either of the two tests mentioned above. The ultrasound's purpose is to evaluate flow and direction of flow . By the pattern and direcdtion of flow, doctors infer a lot about derangements in outflow

It depends upon which veins are used to infuse the chemotherapy. If the port is placed into the jugular veins, it could worsen the outflow obstructions. If it were in the subclavian vein, it could also cause damage that vein and worsen CCSVI.

apologize only for ignorance you choose not to correct

LOVE that! (your quote.) (it is yours, right?) When I repeat it, I want to be able to give credit as due...

Hey Dr S,

in one discussion, Dr Zamboni said that if a patient has had two unsuccessful balloon angioplasty procedures, their problem jugular vein could/should (?) be repaired using surgery. Do you think this is true for high jugular stenoses? I had assumed my high jugular stenosis could not be surgically repaired (I thought it was in my skull)...but your comment here indicates the high jugular region is just below the skull...so maybe still quite accessible?



Helen

Normally this is done through a normal IV in the arm which is removed after the infusion.

_________________
Everybody here brings happiness, somebody by coming,others by leaving.  PPMS since 2000<br />

Helen[/quote

Helen
as you know, i am not a practicing surgeon, thus i do not want to be definitive, but i do not think repair of the upper vein is a likely option. It is really not accessible

thanks for clarifying nunzio, i was speaking about chemotherapy in general, not about an ms drug

i wrote it up sitting around a campfire while reading tims on my phone on july 4 2010, trying to figure out why my Fourth of July photo did not show up on tims

i apologize, i could not figure it out!