fogdweller wrote:Dr. S, I have been greatly concerned over the definition of CCSVI and the degree of variability between patients. Many contributers here and on other threads talk of whether a person has CCSVI or not as if it were a simple thing like wether they had two kidneys or not.
Is it that simple and the easily determined between individuals? It seems to me that every person's veinous system is unique and very complex, and some may be very sensitive to small disruptions and others relatively insensitive to the same disruption. A blockage at one location might be very problematic for one patient and relatively benign for another. Similarly the testing and imaging techniques employed might find problems in a patient where different imaging technique in the same individuals, or different definition of CCSVI might find the opposite. Is that correct?
Did you and your collegues reach a consensus as to what constitutes CCSVI and what imaging protocol to follow?
Also, did you discuss how you would conduct a clinical trial to blind both patients and physicians?
I appplologize if the answers to these questions are on the video of the conference, but I haven't been able to find that.
This was dropped many pages baci while you were away. Sorryfor the repeat, but I am still intertested in this issue.
ccsvi is a term coined by dr zamboni
chronic meaning occuring repeatedly over a long time
cerebrospinal venous pertaining to the brain and spine
venous insufficiency meaning that the venous outflow is insufficient for the needs of drainage.
he detects that by ultrasound which shows reflux up into the veins that should be draining down toward the heart
it is a diagnosis made by US. its consequences in the brain are a hypothesis. several patterns of insufficiency have been defined. how they reflect neurological effects is not yet clarified