HappyPoet wrote:Quick...... a question.......... reposted from earlier............
Dr. Sclafani, what do you think is next for those pwMS who have had venoplasty the maximum number of times?
Thank you very much!
Johnson wrote:What is the maximum number of times?
Since I have asked a question, I would just now like to take the opportunity to thank you, Dr. Sclafani, for your dedication to the study and remedy of CCSVI. Thank you for your sacrifices, great and small.
i do not think that there will be an absolute number of times that the veins can be dilated. Rather i think that repeated dilatation is going to be the norm. I predict that it will become routine for some MSers to have periodic dilatation at intervals and that surveillance will be necessary so that interventions are done before symptoms return. It is unreasonable at this early stage to expect a one time fix.
At some point the congenital deformity of the wall may be replaced by scar tissue that becomes too resistant to dilatation. Similarly stents are likely to have the same problems, with intimal hyperplasia and in-stent stenosis becoming resistant to dilatation.
At some point i suspect that we will need to add some things to angioplasty, either drug, or energy or structure, to reduce the frequency and degree of restenosis.
When will that be necessary? when repeated venoplasty becomes too expensive, too burdensome and too frequent to be practical.
This will all need to be worked out as we go along.