Is it possible to have reflux with a single stenosis? Maybe some of us who have had very mild and very slowly progressing disease have only a single obstruction?
If you only have one stenosis, you might have the reflux but I don't think you'd have the overall slow flow.
And without the slow flow, you wouldn't have the hypoxia. Without hypoxia, no MS?
Or with the reflux, you'd have endothelium weakening near the reflux but not everywhere else. Maybe when there are two stenoses, the slow flow contributes to weakening of the endothelium more overall?
There are few cardinal rules in CCSVI. The first and most important is
Never argue with Zamboni findings
If Zamboni states pattern D requires only the Azygous vein involvement the only thing you can do is to understand why that is.
All other patterns (A,B and C) require 2 vein being involved and if a Jugular vein is involved then another vein has to be involved to validate the pattern.
My explanation is that the brain has 4 blood vessel draining it.
So if only one is blocked the blood can still drain from the other 3.
The spinal cord has only the Azygous vein to drain from and a lesion there has therefore more of an effect on it.
At any rate we are not arguing if the person has MS. We know he or she does, so even if there was only one lesion in the jugular vein noted I would have that dilated considering there could be unknown contributing factors
(iliac vein, renal vein or others) and improved blood flow to your brain/spinal cord can only help if you have MS