Title is: "Probing the etiology of neurological diseases using iron as a biomarker of vascular damage"
He set 3 hypothesis in his document, which has to be proven:
here you can download it:Damage to the vascular system may play a major role in a number of key neurological diseases than has heretofore been thought. ... This proposal will highlight the need to rethink the role of both arterial and venous disease in aging and cancer for the former and MS, stroke and traumatic brain injury (TBI) for the latter. Therefore, my main focus is on the role of vascular damage in neurological diseases and the overarching hypothesis of this proposal is:
Hypothesis One: “A major cause of diverse neurological diseases is vascular damage, the effects of which can be seen with magnetic resonance imaging (MRI).”
Hypothesis Two: “Iron can serve as a surrogate marker for tissue damage, it can be seen in the form of ferritin and hemosiderin using SWI and will directly show the presence of vascular damage.”
Hypothesis Three: “Monitoring the early involvement of the microvascular system will make it possible to discover the etiology/pathogenesis of these diseases, to diagnose them more effectively at an earlier stage and hence to treat them more successfully.”
http://www.ms-mri.com/grants.php
alex