IHateMS wrote:does MT always result in clots?
From my limited understanding the answer is no. Most people with MT are asymptomatic. Which makes it kind of insidious if it is indeed a risk factor for worse MS.
Your explanation is spot on Rokkit. For facts about May-Thurner and some commentary see below:
Most people are asymptomatic with May-Thurner Syndrome. Therefore it is usually undiagnosed, and (if you don't have a blockage in the azygous system) typically not a problem because the blood will just flow through a different outlet to the heart.
The more serious cases do result in Deep Vein Thrombosis or clots in the leg veins, which result in swelling, coloring of the leg and pain/weakness.
Most cases of May-Thurner Syndrome do go undiagnosed, and therefore, though reported to be between a 2% - 5% issue (usually in young women in their 20s - 40s), studies have found it to be much more prevalent.
May-Thurner alone results in poor circulation through the leg veins system (if you believe output = input) and thus causes weakness, numbness, and pain. And blood refluxes from the blockage in the Iliac Vein thus slowing down the entire system. (Again here's that common sense/following simple logic thing that some people on this board and who dismiss CCSVI as junk science don't seem to have).
As Rokkit said, since blockage of the Iliac Vein (associated with May-Thurner) forces blood through other systems to get back to the heart, if the azygous is blocked (as common in MS) you are at a SIGNIFICANTLY greater risk for problems. Thus studies have shown patients with MS AND other vascular problems are at a significantly higher risk to quickly progress as it relates to MS.
What I don't get is why they can't put two and two together ('they' being people who cant separate CCSVI and MS) and say gee I wonder WHY people with a vascular problem are more likely to have "worse" MS (could it be MS has something to do with the vascular system - like I said "geniuses"), and who cares if they have MS if they have a vascular problem. Treat that - treat the vascular part.
I don't think May-Thurner is going to be a lot of the answer for MANY people, but it was for Barb Farrell, my wife, and now Katie41. I'm glad we caught it after less than 6 months of my wife's diagnosis - but don't let me sway you ... you should probably listen to the 4 people on this board who don't want you to get treated for a vascular condition SEPARATE from its impact on MS.