My undeveloped hypothesis of bacterial infection being at the root of "MS" and CCSVI might provide some explanation;
Invasive procedure triggers immune response - which may temporarily (or, more permanently) boost the immune system, and suppress the infection. The natural cortisone in the body is also part of the response, and there might be a temporary alleviation of inflammation, providing a remission. The heparins before and after the procedure might also play a part (were there not studies in using heparin as treatment, which showed some benefit?)
I get stuck that some people get better and stay better, some have moderate benefit, some none, some worse... What is the difference? Could it be differences in the immune system affected by a myriad of factors in each person's life - diet, stress, genetics, etc.
Why are they testing for Lyme disease at some facilities, and sending away those who have Lyme? They cannot be certain that those who test negative for Lyme are actually not false negatives.
I would be very interested to see extensive questionnaires before treatment that cover these factors and others. We might just find the key in that mound of data.
There are all sorts of diets aimed at "MS" - Swank, Best Bet, etc., and they all have common denominators (pH); cut red meat, dairy, sugars, carbohydrates, and other such elements that feed bacteria. Lyme bacteria prefer low oxygen, and can affect endothelial cells, so what's to say that they do not cause stenosis - to create the best environment for their survival and proliferation (hypoxic)? Body pH plays a role. Some bacteria control the pH environment within their cell walls, and render anti-biotics ineffective. Bacteria can be transmitted through the placenta, sperm, ova and breast milk too, which could offer some explanation of the congenital venous malformation hypothesis
No doubt that PTA can provide profound relief to many with "MS". It seems certain that there is a connection, but there are still so many different outcomes, that there must be something else involved. I have had two PTA's with very different outcomes. The difference is that the first was in June, with long, sunny, warm days (I am very happy at that time of year), and other than all of my "MS" symptoms, I was feeling very good. I felt brilliant afterward. I noticed the effects start to fade very soon (days) after, and I started getting a tad depressed (so did my immune system) as the symptoms returned. When I had my second procedure, it was October, with the days turning more gloomy (and my mood). I was sick, and exhausted before, and I had basically no improvement, other than slightly better balance. I was still sick and exhausted for weeks after, and I feel that I might better to have not even bothered with the second round. So, I am trying to kill off bacteria before my next PTA, and to be as healthy as possible. Hopefully it will be warm and sunny.
Just more mumbling from out of the box ideas inc.
My name is not really Johnson. MSed up since 1993