I would argue that this process is not divorced from Vitamin D
We can read many studies and opinions on NO and most of my reading has said that NO is made in the endothelial layer of the vessels.
Human skin contains large stores of nitrite (NO2) and nitrate (NO3). The researchers note that while nitrate is "biologically inert", the action of sunlight can reduce it to active nitrite and nitric oxide (NO).
1eye wrote:Plus if people already have enough vitamin D, how much sunshine they get isn't so important. It is only while they are out in the sun, and for about an hour after, that there is more nitric oxide. But using the smooth muscle more often to do this dilation seems to have an effect on mortality. So sun is more important for everybody than adequate D is for "MS"/CCSVI.
They are saying there is insufficient evidence to warrant checking everyone's Vitamin D level, but more than enough to check it for certain groups such as pwMS, diabetics, during pregnancy, early childhood, elderly and so on, just not everyone unless they have an identified risk factor linked to vitamin D.NZer1 wrote:Hi Ed, what does this part of the article mean?
"no evidence currently exists to support screening at a population level"?
It would seem that they don't really know what is ideal and that they are assuming that Vit D has an effect if it is low and it sounds like they don't know whether Vit D is more than co-factor with or without influence or significance on a disease commencing?
Nigel, first we need to change your screen name to Antipodean Skeptic. :>)NZer1 wrote:I see the words risk factor and or co-incidence and co-factor used in most studies of degenerative disease and have talked to many of the top people in MS and they are non committal on the risk factors and speak of them as red herrings.
So when I see these statistical findings or mathematical equations I often wonder whether Science has come to a dead end with the singular thinking of one item influencing degenerative diseases and realising that it is very complex and requires many factors and many combinations that can also contradict each other, often.
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