The tablets I have are 500mg, and the starting dose is 2 a day, and I have read on the web that some suggest a lot more. The leaflet indicates a change should occur after about 10 days.One HE tablet contained 90 mg bromelain, 48 mg trypsin and 100 mg rutosid
and there is a lot more in it.After adjusting the baseline values of either group to 100%, a statistically significant difference in favor of the enzymes was demonstrated from the sixth month (p < .01 ), an even highly significant difference at end of therapy (p < .001 ).
If the difference at baseline is judged as clinically so relevant that a direct comparison during the course of the therapy is not acceptable, there is nevertheless a difference in favor of the enzymes in the change of the Kurtzke scale: whereas the value improved until the last available vaIue in the enzyme group by 24.2% (from 3.3 to 2.5), it worsened in the corticosteroid group by (-)2.2% from 4.5 to 4.6.
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