Dr Paul Thibault has a Catalyst TV program screening tonight (23 rd August 2012) in Australia. http://www.abc.net.au/tv/guide/abc1/201 ... 200123.htm
It's widely accepted that Multiple Sclerosis (MS) is an autoimmune disease. The cause of MS is unknown and there is no cure. But some maverick doctors contend that MS is triggered by an infection which can be treated. It's believed that a common bacterium, Chlamydia pneumoniae can infect blood vessels in the brain and spinal cord and ultimately lead to nerve damage. Maryanne Demasi meets the doctors who are at odds with neurologists in proposing that an early diagnosis of MS could provide a cure with something as simple as antibiotics."
I have made an appointment for a Doppler Ultrasound check and a sit down with Paul on Wednesday 29th August in Newcastle Australia, after months of discussions about his findings and the people he has treated. I personally have a positive test results for CPn using the NAC self test which Paul has said " Nigel, you almost certainly have a chronic active Cpn infection and this may be the cause of the MS and CCSVI. "
Quote from Paul,
" The CPn intracellular bacteria affects both the lining of the veins and from there spreas to the surrounding nervous tissue. This is the reason why the MS lesions are predominantly around the veins as shown by a number of pathologists explaining the peculiar distribution of MS lesions. Whilst Schelling atributes this to mechanical effects of "back-jets", I favour an infective causation spreading along the veins to involve the neural tissue, as I believe epidemiological evidence favours this pathogenic mechanism. Schelling rightly criticizied the concept of infection, but he assumed that infection would spread from the arterial side of the circulation which it does in general with viral (eg EB virus) infections. But gram -ve intracelluar pathogens such as Cpn (and spirochaetes to a lesser extent) can spread by the lymphatic system and veins. I also check for Chlamydophila trachomatis as I suspect this may be involved in a smaller subset.
Cpn is widespread throughout society as a common respiratory infection and most people will come into contact with it at some time. Why only a very small proportion develop MS is unknown, but may be related to Vitamin D levels at the time of initial infection and other unknown factors. Kurtzke predicted this with his extensive epidemiological studies and he favoured the idea that it waas mainly one infective agent, rather than a larger number.
The reliability of the NAC test is yet to be determined and I am accepting David Wheldon's opinion on this. It would certainly make an interesting study. The article I would recommend you to read is:
Kurtzke JF. Epidemiologic evidence for multiple sclerosis
as an infection. Clin Microbiol Rev 1993;6:382–427"
" I have recently seen a number patients have good results with the CAP with slow but progressive IMPROVEMENT in their symptoms, and today one younger patient showed significant improvement with almost normalisation of the blood flows after 5 months without having had any venoplasty. At present I am referring about 50% of pwMS on for venoplasty based on the Doppler scan (which in a recent case was more accurate than CT venography) and whether the patients wishes to proceed that way."
"You don't need to go to your GP to do the NAC test. It is unlikely that he/shw will know anything about it. It is a clinical test that you do yourself see : http://www.davidwheldon.co.uk/NAC.html
. You just need to get a bottle of N-acetyl cysteine (NAC) and take 2 capsules twice daily for 3 days. If you develop respiratory symptoms or worsening of your MS symptoms then you probably have an active CPn infection going on. Getting the NAC can be difficult as not all pharmacies or health Food shops have them but they can be obtained over the internet from companies such as Evidencia."
"I think the reason why IVUS has not taken off in Aus/NZ is realted to lack of interest by the interventional radiologists in ultrasound in general. CCSVI is probably one of the few areas where it has much application. It was initially introduced into general phlebology about 20 years ago by Pauline Raymond-Martimbeau, but never took off."
"I (or my vascular sonographer in fact) do a slightly different protocol to Zamboni which I believe is more objective and correlates very well with subsequent MRVs and venography. We don't specifically measure vein diameters as these are so variable from moment to moment, instead we concentrate on blood volume flows which incorporates vein diameter within the calculation anyway. But we also measure the BVFs from the 3 segments of the IJV (Zamboni doesn't record any BVFs) as well as the vertebral veins, and we record the global cerebral arterial volume flow (as described by Doepp et al) which is very useful to monitor progress post venoplasty. With this method I believe we get better quantification to measure progress over time. I am currently preparing an article on this method which will include results of a pilot study before and after venoplasty."
The quotes above are all with Paul's permission and are excerpts from pm discussions on Face Book over many months.
Paul's Face Book link BTW is,https://www.facebook.com/paul.thibault.37
My CCSVI in NZ Face book link is,https://www.facebook.com/pages/CCSVI-in ... 1636357984
Hope you are well,