This Is MS Multiple Sclerosis Community: Knowledge & Support

Welcome to the world's leading forum on Multiple Sclerosis research, support, and knowledge. For over 10 years, This is MS has provided an unbiased community dedicated to Multiple Sclerosis patients, caregivers, and affected loved ones.
It is currently Sat May 18, 2013 2:37 pm


All times are UTC - 8 hours [ DST ]




Post new topic Reply to topic  [ 1 post ] 
Author Message
PostPosted: Fri Aug 31, 2012 8:52 am 
Offline
Family Elder

Joined: Mon Jan 04, 2010 4:00 pm
Posts: 8505
Work done in our jugulars may be more prone to clotting than work done in other veins. Jugulars collapse in size when we are upright, limiting the flow. In some patients, flow is slow in the jugulars even after venoplasty, and that slow flow can contribute to clotting. PwMS may also have a tendency toward more coaguable blood.

So perhaps a platelet test should be used in CCSVI patients? I was reading about platelet testing here, although this was not in CCSVI patients:
http://www.medpagetoday.com/MeetingCove ... id=5517461
Quote:
In the 798-patient MADONNA study, patients whose antiplatelet therapy was guided by a platelet function test had a nearly eight-fold decrease in risk of stent thrombosis versus controls, according to Jolanta Siller-Matula, MD, PhD, from the Medical University of Vienna, and colleagues.

The second study, RECLOSE-2 ACS, found that "global platelet reactivity," which tests for both clopidogrel and aspirin responsiveness, was able to identify a cohort of patients at increased risk.

The 9% of global nonresponders in the RECLOSE-2 ACS study had a significantly higher risk of cardiovascular ischemic events and cardiac death compared to those without a global high platelet reactivity, according to Rossella Marcucci, MD, of the University of Florence in Italy, and colleagues.

Antiplatelet drugs Clopidogrel and/or aspirin are sometimes prescribed after a CCSVI treatment or in combination with Pradaxa or an anticoagulant. If 9% of patients are nonresponders to Plavix or aspirin, that is a significant amount of people who would not be getting any anticoagulation or antiplatelet effect at all if only aspirin or Plavix is prescribed. Outcomes of clotting can include fully occluded jugular veins or pulmonary embolisms.

If a doctor prescribes only aspirin and/or Plavix, it might be a good idea to ask if platelet testing can be done, or to consider Pradaxa or other anticoagulants that work differently than the antiplatelets. Not meant as medical advice...


Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 1 post ] 

All times are UTC - 8 hours [ DST ]


Related topics
 Topics   Author   Replies   Views   Last post 
There are no new unread posts for this topic. CCSVI TESTING / TESTS CCSVI *CANADA*

SickButHappy

2

2290

Fri Apr 30, 2010 9:48 am

eveable View the latest post

There are no new unread posts for this topic. Advice on testing CCSVI

dado84

2

1175

Mon Jan 25, 2010 7:08 am

dado84 View the latest post

There are no new unread posts for this topic. LDN and diagnostic testing for CCSVI

ngocky

3

1083

Sun Jan 31, 2010 7:21 am

thisisalex View the latest post

There are no new unread posts for this topic. Testing for CCSVI in Boston?

Selmahope

7

1558

Sat Mar 20, 2010 5:08 am

AndrewKFletcher View the latest post

There are no new unread posts for this topic. CCSVI testing and treatment

Ned

1

836

Wed Apr 21, 2010 10:21 pm

hwebb View the latest post

 


Who is online

Users browsing this forum: No registered users


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum

Search for:
Jump to: