Last week I started on 150 mg Doctor's Best Bentofamine and I was rather surprised to notice better mobility, better eyesight, less joint pain... then yesterday I took 300 mg, and was able to hold onto utensils like a fork or knife with much greater ease. Today, I took 600 mg and I have noticed greatly increased sensitivity of the bottom of the feet. And I can reach! Without pain! My left arm is moving in ways that it has not moved for two years! It is far far easier to control my right arm, navigate the wheelchair. This is fu**cking amazing actually. My results with this exceeds my results with the hyperbaric chamber. Now I do have to add a caveat as I have been doing CPAP therapy, but prior to this Benfotinamine, I was actually more tired because I am not tolerating the mask (I am now on my third one). Now maybe this CPAP is having some form of beneficial outcome, but until now I certainly haven't noticed any improvement in mobility... now there's a couple reasons why this stuff could help the way it is helping me. One, thiamine is what you use to make acetylcholine, which is a major neurotransmitter that assists nerve communication... you need thiamine to process sulfur, and anyone that knows by postings of years gone by, you might remember that sulfur and I do not get along. On last night's conference call, once again Dr. Scott was on the line and he said it was absolutely criminal that they were not having diabetics take 150 mg a day to prevent complications. He said he used it in his practice 20 years and never had his diabetic patients lose a limb or develop kidney problems. This stuff has been around for 50 years. Years ago, I had an Organix acid test that pointed out that I needed B1 (thiamine) three times a day... but of course, things like mercury and lead and cadmium screw up the enzymes that help you convert B1 to its active form. Considering that I cannot convert thyroid hormone from T4 into T3, maybe I should not be so surprised that thiamine is also messed up.
Mercury oxidizes B1, and I have known that forever, but I did not know you need thiamine to make stomach acid. I did not know that thiamine is critical to the blood brain barrier, that deficiency causes a breach in the BBB. Thiamine is necessary to process magnesium properly. Anyway, I am hoping my results are not transient like they are from the chamber, although last night results did last until bedtime. As far as I can figure out, it is taking about four hours from the time of dosing to the time that I see much much better mobility. And I sure as hell hope that is not like my phlebotomy where I got amazing results for about 40-45 days and then it all disappeared. Thiamine seems to be heavily involved in vascular health also, maybe because it helps carbohydrate metabolism. You need more thiamine if you have sleep apnea, and if you have a lot of Candida it releases a toxic metabolite that screws up the enzymes that convert thiamine to its active form. I paid around $15 for 120 capsules of 150 mg. I will keep you updated!http://www.innovative-diabetic-diet.com ... pathy.html
Some animal studies have shown a decrease in pain with a combination of vitamin B1, vitamin B6, and vitamin B12.
The fat-soluble form of vitamin B1, called benfotiamine, has been used effectively to treat alcoholic and diabetic neuropathies.
The most marked pain relief from benfotiamine occurred in patients with diabetic neuropathy after only a three-week trial period.http://www.whfoods.com/genpage.php?tnam ... t&dbid=100
Nervous System Support
Vitamin B1 also plays a key role in support of the nervous system, where it permits healthy development of the fat-like coverings which surround most nerves (called myelin sheaths). In the absence of vitamin B1, these coverings can degenerate or become damaged. Pain, prickly sensations, and nerve deadening are nerve-related symptoms that can result from vitamin B1 deficiency.
A second type of connection between vitamin B1 and the nervous system involves its role in the production of the messaging molecule acetylcholine. This molecule, called a neurotransmitter, is used by the nervous system to relay messages between the nerves and muscles. Acetylcholine cannot be produced without adequate supplies of vitamin B1. Because acetylcholine is used by the nervous system to ensure proper muscle tone in the heart, deficiency of B1 can also result in compromised heart function.
What are deficiency symptoms for vitamin B1?
Because of its ability to disrupt the body's energy production, one of the first symptoms of vitamin B1 deficiency is loss of appetite (called anorexia) that reflects the body's listlessness and malaise.
Inability of the nervous system to ensure proper muscle tone in the GI tract can lead to indigestion or constipation, and muscle tenderness, particularly in the calf muscles.
Other symptoms related to nerve dysfunction are commonly associated with thiamin deficiency, since the myelin sheaths wrapping the nerves cannot be correctly made without adequate thiamin. These nerve-related symptoms include "pins and needles" sensations or numbness, especially in the legs.