Gilenya is supposed to be more 'effective' at reducing lesions, reducing attacks, slowing brain atrophy.
I'm on it. I'm more afraid of MS disability than I am of very rare bad outcomes.
Side effects for me were heart rate slowing on the first dose from mid 70's to 55 beats per minute. That reversed.
I also experienced four days of bad fatigue and about six of very sharp tiny pains in random places plus muscle aches. All better now.
I have a spouse but no kids. If I had small children I would wonder about taking Gilenya.
The bad rare side effects are supposed to go away on stopping the drug,
but they would interfere with life a lot until they got better. Depending on who you listen to, either two or 11 people died
out of the at least 50,000 taking the drug. I'm sure there are a few more unreported deaths.
The long term risk I see is infection. My plan is to be off Gilenya by 60, sooner if I start to get sick a lot.
I never took Copaxone. The needles and the skin reactions and the pain were enough for me to not try it first.
Also, I had MS undiagnosed for at least a decade and I wanted to start with something stronger.
As far as I know, Copaxone doesn't risk any extreme side effects, just chronic annoyance.
Good luck, whatever you choose.