hey there,
can't find it published but:
Quote:
In our study, Nutrition, neuromuscular electrical stimulation (NMES) and secondary progressive multiple sclerosis (SPMS), we follow twenty individuals for thirty-six months as they use the same treatments I developed for myself. The first eight have already completed the first twelve months of the intervention, with favorable preliminary data, (one of our subjects is moving from cane and walker dependence to beginning to jog again), which was presented at the 2011 Neuroscience Conference in Washington, D.C. November 13...
other than that it's just the case study measures, great results but n=1 and too subjective:
Quote:
Table 2. NARCOMS survey questions and patient responses
Date questions answered............................11/23/2005 6/2/2006 11/28/2006 5/5/2007...........12/12/2007............4/30/2008
Compare your overall MS symptoms now
with what you experienced 6 months ago.
Is your MS:......................................................Worse......Worse.........Worse....Worse...Somewhat Better..........Much Better
Rate your MS symptoms overall ....................Moderate...Moderate....Moderate.Moderate................Minimal....................None
Fatigue symptoms........................................Moderate.....Severe...........Total......Total...............Moderate.....................Mild
and this one on just the neuromuscular component...
Quote:
Mean of years of diagnosis was 10.4 (range, 4–15), and mean EDSS score at presentation was 5.9 (range, 4.5–6.5). Mean of days of NMES was 140 (range, 22–495). Mean EDSS scores improved by 0.78 (range, 0–2.0).
back on the copper track..
Role of copper in human neurological disorders
http://ajcn.nutrition.org/content/88/3/855S.fullfull text would be nice on this one. wish i could see the coexisting nutrient deficiencies...
Clinical significance of the laboratory determination of low serum copper in adults.
http://www.ncbi.nlm.nih.gov/pubmed/17727313Abstract
Quote:
BACKGROUND:Low serum copper is often indicative of copper deficiency. Acquired copper deficiency can cause hematological/neurological manifestations. Wilson disease (copper toxicity) is associated with neurological manifestations and low serum copper, with copper deposited in tissues responsible for the toxicity. Low serum copper can also be observed in some carriers of the Wilson disease gene and aceruloplasminemia. This study was undertaken to determine the clinical significance of low serum copper.
RESULTS:In six of the 57 patients with low serum copper, the low copper was due to Wilson disease. In the remaining 51 patients, copper deficiency due to an underlying cause was identified in 38 as a reason for the low serum copper. The most commonly identified neurological manifestation of copper deficiency was myeloneuropathy. Coexisting nutrient deficiencies and hematological manifestations of copper deficiency were often but not invariably present.
CONCLUSIONS:Copper deficiency, Wilson disease (or a carrier state), and aceruloplasminemia are all associated with low serum copper. The presence of coexisting neurological or hematological manifestations that are recognized sequelae of copper deficiency should be considered prior to making a diagnosis of copper deficiency. Gastrointestinal disease or surgery is a common cause of acquired copper deficiency. Even in patients in whom low serum copper is indicative of copper deficiency, the cause of the copper-deficient state may not be evident.
i wish you were able to get that urine ceruloplasmin test. it makes no sense for you to have low copper and then feel worse when you add a supplement.
that said, do you have this:
http://en.wikipedia.org/wiki/File:Kayse ... r_ring.jpgas for nystagmus wow there's loads you can do to treat that. .
Nutritional nystagmus in infants.
www.ncbi.nlm.nih.gov/pubmed/3928866Suspicion of a B vitamin deficiency resulted in correct diagnosis of dietary deficiency and/or enzymatic defect. In both instances, dietary treatment with B vitamins resulted in resolution of the nystagmus and improved growth and development of both individuals
Nystagmus: Overlooked Causes and Treatments
www.ctds.info/nystagmus.htmlMany web sites on nystagmus do not mention the role of nutrition as a possible cause of the disorder. However, there are a significant number of medical papers on nystagmus being caused by nutritional deficiencies and cured by the correction of those same nutritional deficiencies, usually magnesium or thiamin.
.....Magnesium metabolism in childhood.
.....
http://www.ncbi.nlm.nih.gov/pubmed/8264 ... t=Abstract Quote:
Hypomagnesemia in childhood is relatively frequently noted ... Myopia and horizontal nystagmus are often present
.....Magnesium deficiency. Etiology and clinical spectrum.
http://www.ncbi.nlm.nih.gov/pubmed/7020 ... t=AbstractQuote:
The manifestations can be divided into the following categories: totally non-specific symptoms and signs ascribable to the primary disease; neuromuscular hyperactivity including tremor, myoclonic jerks, convulsions, Chvostek sign, Trousseau sign (rarely), spontaneous carpopedal spasm (rarely), ataxia, nystagmus and dysphagia; psychiatric disturbances from apathy and coma to some of all facets of delirium; cardiac arrhythmias including ventricular fibrillation and sudden death; hypocalcemia which is responsive only to Mg therapy; and hypokalemia which is not easily nor completely corrected without Mg therapy.
you can read on for yourself re the studies on nystagmus and b vitamins. also fyi magnesium activates b vitamins. may regulate action of b6 and b12 (dog study). mag deficiency may aggravate thiamin deficiency (case study). both b6 and b12 are related to mood and magnesium itself to anxiety so that could be part of how you're feeling today.
Extracellular magnesium regulates effects of vitamin B6, B12 and folate on homocysteinemia-induced depletion of intracellular free magnesium ions in canine cerebral vascular smooth muscle cells: possible relationship to [Ca2+]i, atherogenesis and stroke
http://www.sciencedirect.com/science/ar ... 4099006837Aggravation of Thiamine Deficiency by Magnesium Depletion: A Case Report
http://onlinelibrary.wiley.com/doi/10.1 ... x/abstractgood to see all that info on fats and protein. will check out the amounts for 230g salmon, grilled. sure you can send the info on the chicken and salmon tomo.