MSRV Retrovirus, phase 2

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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Thu Dec 04, 2014 7:06 am

Hello,

Here is the information regarding 2a phase :

http://www.geneuro.com/en/news/press_articles.php

The target was only to evaluate the safety of the doses.

I don't have any indication about the fact I was in the placebo arm during the first phase or not.
However, I took the extension of this first phase including placebo, with 100% warranty in this second phase I received the product.

I took only 2 mg/kg which is probably not enough.
As far as I know, roughly 80% of the patients noticed stabilization, even improvements for some cases. All were in progressive stage.

The doses will be higher in the future, roughly 20 mg/kg I think.

Have a good day,

Fred
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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Mon Jan 26, 2015 5:55 am

Hello

The 2b phase should start this summer.

Some necessary tests have been launched with higher doses (15 and 30 mg/kg).

As far as I know, no problem at this moment.

Have a good day,

Fred
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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Tue Jan 19, 2016 5:13 am

The 18th of december 2015, Geneuro annonced starting of Phase 2b.
Preliminary results at the end of 2017.

You could find a video here : http://www.geneuro.ch/en/news-press
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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Mon Jan 30, 2017 11:35 pm

Hello Everybody.

The 2B phase started in Europe; 260 patients involved, for relapsing MS.
First preliminary results will be given in October.
A 2B phase for progressive MS should start in US very soon.
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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Wed Feb 01, 2017 7:59 am

Bottom of the window, please click for english subtitles

https://youtu.be/1XIstjFMYh8
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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Fri Feb 03, 2017 1:43 pm

Video done in 2014 by Hervé Perron, who was at the origin of this finding.

Same thing, please click on the window bottom to get english subtitles

https://youtu.be/M1zSbV7PiVw
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Re: MSRV Retrovirus, phase 2

Postby Fred1208 » Sun Oct 08, 2017 9:02 am

Geneuro gave preliminary results at 6 months for their 2B study.

At 6 months, there is no difference between their product versus placebo.

BUT

1 there is one year study
2 the study continues, the partner SERVIER still supports them.
3 Geneuro immediately indicates that the action process could be longer. in other terms, it coulde be possible that 6 months could be a too short period to see anything as positive results.
4 Geneuro is going to present at ECTRIMS in paris ( https://www.ectrims-congress.eu/2017.html ) on the 28th of october these 6 months results. It seems they have got data indicating that the action mode is lower ( http://www.geneuro.com/data/news/geneur ... ims-en.pdf ).

Stay tuned.

If there is a confirmation of positive results in Januarry/February 2018, a 2B study will start for progressive forms in US.
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