Zinc and copper in multiple sclerosis
The serum concentrations of zinc and copper were measured in 50 patients with multiple sclerosis. Lower serum zinc levels were found compared to age- and sex-matched controls. In younger patients low serum copper concentrations were noted.
*that is one great 'n'!! **things that make ya go hmmmSerum vitamin A and zinc levels of healthy people in northeast Thailand
The average serum zinc level of the population (n=1113)* was 18.20 μmol/l (95% CI= 18.05-18.36). There was no significant difference in the zinc levels between males and females, i.e. 18.20 μmol/l (95% CI=17.90-18.36) vs. 18.36 μmol/l (95% CI= 18.05-18.66). The zinc level tended to decrease significantly as age increased, particularly in the male population (p<0.05)**.
Serum uric acid levels in multiple sclerosis patients correlate with activity of disease and blood–brain barrier dysfunction
Several findings suggest lower levels of serum uric acid in multiple sclerosis (MS) patients. ... Sixty-three definite RRMS patients and 40 controls ... MS patients were found to have significantly lower serum uric acid levels (193.89 ± 49.05 μmol/l; mean value ±SD) in comparison with healthy donors (292.7 ± 58.65 μmol/l; P=0.000) ... MS patients with relapse had significantly lower serum uric acid levels (161.49 ± 23.61 μmol/l) than MS patients with remission (234.39 ± 41.96 μmol/l; P=0.000) ...
The multifaceted and widespread pathology of magnesium deficiency
http://www.sciencedirect.com/science/ar ... 7700911332
The range of pathologies associated with Mg deficiency is staggering: hypertension (cardiovascular disease, kidney and liver damage, etc.), peroxynitrite damage (migraine, multiple sclerosis, glaucoma, Alzheimers disease, etc.)...
About the Misdiagnosis of Magnesium Deficiency
...In patients with Mg serum values lower than 0.9 mmol/l Mg, magnesium supplementation is recommended; for patients with values lower than 0.8 mmol/l, starting Mg supplementation is necessary. We recommend that a Mg serum value of 0.9 mmol/l Mg be considered as the lower reference limit, in evaluating symptoms or diseases suspected as being associated with Mg deficiency. In this case, Mg has to be used as a first choice therapy. When symptoms of the MDS are found, patients with serum values of less than 0.8 mmol/l Mg, or better 0.9 mmol/l Mg, ... [not automatically] normomagnesemic.
serum ferritinSELENIUM, VITAMIN E AND COPPER IN MULTIPLE SCLEROSIS
...The Se content of whole blood was low (52.8 ± 11.3 ng/ml) in MS patients from this high-risk area compared to the controls (68.8 ± 11.0). ...
Alpha-tocopherol and NADPH in the erythrocytes and plasma of multiple sclerosis patients. Effect of interferon-beta-1b treatment.
OBJECTIVES: To investigate the influence of interferon-beta-1b (INF-beta-1b) therapy on blood antioxidants (alpha-tocopherol and NADPH) in multiple sclerosis (MS).
METHODS: Patients with relapsing-remitting MS (n = 14) have been studied during 6 months of INF-beta-1b therapy. alpha-Tocopherol was determined by HPLC and UV or electrochemical detection; NADPH was quantified spectrophotometrically. RESULTS: The erythrocyte alpha-tocopherol level was reduced (p < 0.001) before treatment, but had regained the control level by 6 months of therapy.
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