sensitivity to alcohol, codeine and other drugs

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sensitivity to alcohol, codeine and other drugs

Postby kevin4apenny » Mon Sep 06, 2010 6:15 am

HI guys,

Has anyone here found themselves to be sensitive to ALCOHOL or CO-CODAMOL?
I have ALWAYS had horrendous hangovers until I packed in drinking it altogether. I recently found I have hangovers when I take Cocodamol for my (old guy's) bad back and shoulder cramps and NEURITIS.
My OPTIC NEURITIS is also very bad
Currently I am in WEEK TWO of a reaction to Cocodamol: I am 'zonked' with EXTREME DROWSINESS.
Nauseated feeling
I still manage to jog and do my morning exercises so I am strong(ish) but my LEGS FEEL like JELLY and I still 'FEEL' weak......
I am always adding to any blogs that I am going to the GLASGO INTERNATIONAL CONFERENCE on CCSVI in OTOBER 29th 30th. this year, as I am one of the organises hope ysome of you can make it

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Postby shye » Mon Sep 06, 2010 7:00 am

Have you had your zinc levels checked? MS'ers often low, and those with low zinc don'd tolerate alcohol and meds (know from experience! and research).
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Postby lucky125 » Mon Sep 06, 2010 5:16 pm

I am allergic to codeine, fentanyl, and penicillin.

I cannot drink more that a half a glass of wine, too. My husband calls me a cheap date. ;o)

I think my alcohol intolerance may be due to baclofen. My muscles in my arms start to feel weak and warm when I try to drink. I have no trouble with strength in my arms. It's my legs that are effected by my MS. Very weird.

I have said for years, "I can walk or I can drink, but I can't do both!"

Shye, interesting about the zinc. I'll have to get that checked out. I'd love to be able to have a good margarita!

Liberated at Georgetown U. 3/3/10. Subsequent procedures at U of Maryland with Dr. Ziv Haskal 7/30/10, 12/2/10, 5/11/11.
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Postby Bubba » Mon Sep 06, 2010 8:07 pm

my sensitivity to beer has definately increased. Pisses me off to. Used to, I would down 18 and feel fine. Now, i am puttin away 5 and starting to slur words already :x
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Postby MrsGeorge » Tue Sep 07, 2010 12:00 am

I almost never drink so was surprised when I got drunk on half a glass of wine a few weeks back - incresing that to 2 glasses of wine was......interesting! My husband insisted on pushing the wheelchair home!
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Postby jimmylegs » Tue Sep 07, 2010 3:45 am

i second shye re zinc.

relates to optic neuritis. zinc is needed for your body to use vit A for vision.

you can get alcohol induced optic neuritis without zinc 'deficiency', but merely having lower zinc levels.

technically ms-ers don't have zinc 'deficiency' either. it's just low and could be optimized.
Subclinical alcoholic optic neuritis without vitamin deficiency
bahaha world without zinc
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Postby shye » Wed Sep 08, 2010 6:21 am

Yes, I had severe optic neuritis years ago--beginning of this MS stuff.
Years later, found via tests that needed more zinc than usual.
Recently, despite high zinc supplementation, found still LOW in zinc on blood tests., and "fail" the zinc taste test--clearly, still not taking enough.
When I take an immense amt of zinc (over 150, often well over) my eyesight is better--better contrast, color, sharper vision; and walk okay, muscle strengh then okay, etc etc
there are some of us who need huge amts of zinc--wise to get your serum levels checked, as well as take the taste test---and wise to then follow the alterntive literature on this--my drs at the time convinced me it would be harmful to take more than 15 mg zn--lost a lot of time and health by listening to them!
(also, do your homework--if take zinc, have to also take some copper--if not, you will run into further health problems).
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Postby jimmylegs » Wed Sep 08, 2010 6:59 am

brief hijack warning (shye do you have your own regimen thread? if so i'll move this to it)
* * *
shye, your zinc issues have been nagging at me. i went looking and found a protein connection.

interesting abstract (and close to home!):

The Effect of Severe Protein Deficiency on Serum Zinc Concentration of Mice Fed a Requirement Level or a Very High Level of Dietary Zinc
S. M. Filteau and Bill Woodward

Department of Nutrition, College of Biological Science, University of Guelph, Guelph, Ontario, N1G 2W1 Canada

The objective of the present study was to determine the effect of severe dietary protein deficiency on serum zinc concentration in weanling animals fed either a requirement level or a very high level of dietary zinc. Weanling (21-day-old) male and female CBA/J mice were randomly assigned to be fed one of four diets containing either 1.7% or approximately 18.5% protein and either 7 µg (predetermined requirement level) or about 200 µg zinc per gram of formulation. Serum zinc levels were measured after a 14-day feeding period. Dietary zinc content, over the range tested, did not influence the serum zinc level of protein deficient mice, and these animals exhibited serum zinc concentrations which were much lower than the levels found in adequately nourished mice fed the requirement level of zinc (7 µg/g diet). These results indicate that dietary zinc supplementation is unable to restore to normal the zinc status of severely protein-deficient animals. This may be an important factor to consider when studying the effect of protein deficiency on zinc-sensitive physiological processes.

shye i don't know if you have reason to suspect that your protein is down, but you may want to look into prealbumin testing.
link to prealbumin at

FYI, when i finally found and addressed my zinc deficiency i had already been following the protein advice (eg 2 eggs for breakfast! - but not every day, that's for sure) found in the klenner protocol (too bad i'd ignored the zinc info there) and had changed from a vegan to an omnivorous diet.

i think this may have made correcting my zinc an easier task.

also, on the copper front, FYI to any and all readers:

world's healthiest foods - copper ... nt&dbid=53

scroll down the list for the ranking by quality (eg excellent, very good, etc)
calf's liver comes out number one, crimini mushrooms, and the dark leafy greens, (also beneficial for magnesium content) are right up there too: mustard greens, chard, spinach, kale, etc.
bahaha world without zinc
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