sorry to hear you're having a rough time. what kind of symptoms do you have to put up with?
just curious... have you already addressed all the nutritional angles that go with ms? have you had all the bloodwork done and corrected any problems with vit b12, vit D3, magnesium, zinc, and so on?
as for what you tell the transition... do you think you could hang in there at the current job until you secure the new one? i'm sure you could come up with a reason for wanting to make a change, that did not highlight how rotten you're feeling lately.