I suggest we start a discussion with a focus on cellular nutrition, that is vitamin D, blood sugar fluctuations and insulin fluctuations and damage that can cause, the GLUTs and the enormous temperature sensitivity, Metformin, LDN, the liver and what a new liver can do, triglycerine and cholesterol levels, sugar intake, parallels diabetes - MS, etc.
I have seen signs of weakness with my dad that I suffer from now, 25 years ago. More or less simultaneously, he got diagnosed with type 2 diabetes. He takes little or no sugar anymore (my mother tells me his sugar intake was very high just before his diagnosis) and not too much fat, and his pills (Metformin and Glimperid).
We are now 25 years later, he is 84 years old and in excellent health. The weaknesses seems to have gone, vanished unnoticed. A discussion here on TIMS in the autumn of 2010 (with Lyndacarol) has also been the start of this thread. So I know it can be done and I have confirmation from a number of professors from different countries, independent for each other, that it conceptually is correct or at least as plausible as the autoimmune hypothesis ...
Last autumn, my dad had - after a period of severe stress - three attacks of what looks like Meniere. What is that? An autoimmune response behind the ear. When I heard that, this rang the bell for me: nothing autoimmune, but stenoses in the draining veins behind the ear. But he is just fine now
In Dutch, the saying goes "The apple never falls far from the tree". Well, I think that true here as well. I have discussed the matter with endocrinologists and diabetologists, but I'm (still) not diabetic and my hormones are ok. So they say there is nothing they can do for me, I guess they follow the protocols... But I have MS and I think in my case (after the necks veins were opened) the pre-diabetic condition (read the bad T cells from the intestine) is playing tricks on me, and causes a further deterioration..
A related phenomenon that I can not explain is the temperature effect. When it is hot in the summer and I'm at the pool, then I do not walk as good ... But if I take a deep dive in the cold pool and stay in there for a while, then I walk again like a well-oiled machine. Why is that? I think that it is caused by the temperature effect of the GLUTs (an effect that is well known). And that if there is one thing that we must do, it is to ensure that our GLUTs (which are the gates for glucose transport into the cells) stay in a good condition. Where high fluctuations of the glucose level and insulin are devastating... (Lyndacarol, if you still read here: recognise this?). Metformin may help to stabilise the bloodsugar and improve the absorption of glucose by the cells. And I understand that it has no "memory effect" so you can continue to take it.
In the medical world, I run into the big brick wall. Thus, there is need and opportunity here to further explore the links between MS, diabetes, Vitamine D and cellular nutrition..