I will try to recapitulate: What is Multiple Sclerosis?
Multiple Sclerosis (MS) is caused by a faulty immune system that reacts to problems in the intestine (faulty brain-bowel connection). If the gut flora is unbalanced, bad T-cells induced by the gut start to spread in our body through the bloodstream. Here, the over-presence of the segmented filamentous bacteria (SFB) in the gut flora is suspect.
The immune system response to the bowel infection is believed to be the cause of many diseases including diabetes, rheumatic disorders and late-onset asthma. For people with MS, after many years of CCSVI (venous insufficiency in the draining part of the brain) the blood-brain-barrier (BBB) will be compromised causing the protective tissue to become permeable. Bad T-cells can then enter the brain and do their destructive work. In particular, undernourished weakened cells of the eco-system that got infected are targetted. Besides neurological damage in the CerebroSpinal, people with an unhealthy intestinal flora may develop a diabetes-related peripheral neuropathy aggravating the neurological symptoms.
While the unbalance of the gut is mainly responsible for the secondary degenerative phase, in the early Relapse Remitting phase of MS, the immune system may react to virus infection (e.g. Bar-Eppstein) or a periodic reactivation of the Chlamydia bacteria.
1. http://www.congrex.ch/fileadmin/files/2 ... harcot.pdf
, see page 2;
; the results of epidemiological research are very strong!What about our kids? Speed is of the essence
A related question is: what if our kids would turn out to have CCSVI – the genetic component in MS is known. But have no symptoms of MS yet. Is it dangerous for them to have CCSVI? Because the BBB could get under stress with the risk that it finally breaks? After which T-cells can do their destructive work and they would eventually develop MS.
MS patients may certainly benefit from the new insights. But it may be our children that are the real winners of this breakthrough. If they get liberated in good time (assuming they have vascular constrictions of their neck veins draining the brain) they will never develop MS.
With good screening programmes through relatively simple and inexpensive echo-Doppler examination, in the time of a generation, MS may be of the past.The systemic problem
Neurologists believe that CCSVI is a strange term. A vascular specialist knows very well what is CVI, CCSVI is nothing more than CVI (Chronic Venous Insufficiency) for the Cerebro Spinal.
This shows the problem. MS is a disease that transcends beyond the boundaries of the different medical disciplines. MS is caused by a complex of issues; there is not one single cause. It involves neurology, vascular, endocrinology, and diabetology.
Cooperation across the boundaries is easy and automatic for some diseases like cancer, but for MS it is not. The patterns for cross-discipline communication in the field of MS are virtually non-existent. The current division of work and the strict protocols of medical specialists create an important cultural barrier to change.
In addition, the power of the system presents a significant problem. Firstly, so many institutions and so many people from health professionals, science, commerce and government have so much invested in the current system, and therefore have so much to loose by change. Secondly, the public, politicians and patients are almost all conditioned by history to think about health and health care in particular ways. The very things that helped us make such excellent progress in the twentieth century have, paradoxically, now become a major part of the problem.
3. http://www.amazon.com/Turning-World-Ups ... 389&sr=1-1 The challenge is to graduate the system
As there are powerful opposing forces to change, there is risk of developing confrontational positions between medical disciplines. The challenge is to manage a real-life transition as smooth as possible and to fend off the risk of stagnation of the whole system.
This will need to involve another way of approaching MS as a disease. The medical system is deeply entrenched in research, and the research culture is dominant. But as it looks now, MS is more a scientific combinatorial problem than a deep research area that could possibly be unravelled by applying and connecting to each other existing scientific results more vigorously.
As the potential ramifications of current findings are so huge, the medical sector may have lost its fixed Archimedean points from which to exert leverage. Outside help may help accelerate the change process.
4. http://www.thelancet.com/journals/lance ... 1/fulltext