There is the presumption of a relationship between rheuma arthritis, diabetes and MS (which disease is entirely diabetes related) in the sense that all these diseases are autoimmune diseases that originate from the gut.
See for instance: Altered Immunity & The Leaky Gut Syndrome http://www.mold-survivor.com/leaky_gut_syndrome.html
quote: The leaky gut syndrome is almost always associated with autoimmune disease .... An autoimmune disease is defined as one in which the immune system makes antibodies against its own tissues. [well we know they come from the gut...] Diseases in this category include lupus, alopecia, rheumatoid arthritis, polymyalgia rheumatica, multiple sclerosis, fibromyalgia, chronic fatigue syndrome, Sjogren's Syndrome, vitiligo, thyroiditis, vasculitis, Crohn's Disease, ulcerative colitis, urticaria;hives, diabetes and Raynaud's disease.
Now, guess what? Last week I was told that the latest medication for combatting rheumatic diseases works via the gut!
Would you believe it?!
I searched a bit and found this:http://www.lef.org/magazine/mag2012/feb ... ack_01.htm
SummaryA team of Stanford researchers recently demonstrated that both rheumatoid and osteoarthritis are triggered by an abnormal immune response.
Arthritis is traditionally treated with side effect–prone anti-inflammatory and immune-suppressing drugs. A unique compound has been developed that is capable of safely and naturally desensitizing the immune system so that it “learns” to stop launching the attacks on aging joints that cause arthritis pain and swelling.
Through a pathway known as induced oral tolerance, undenatured type II chicken collagen retrains the immune system to correctly recognize exposed cartilage proteins as the body’s own tissues—instead of incorrectly seeing them as foreign microbes—thus preventing the inflammatory and destructive attack that causes osteoarthritic joint pain and stiffness.
Supported by the anti-inflammatory action of a novel composition of AKBA-enriched Boswellia serrata—and further boosted by the joint-rebuilding nutrients, glucosamine sulfate and boron, 40 mg a day of undenatured type II chicken collagen may halt the abnormal immune process that strikes arthritis sufferers.
The exciting news is a novel intervention has been identified that safely regulates the immune system to protect aging joint tissue from autoimmune attacks....
If T-cells are given adequate preparation, however, they can be “taught” that a specific molecule is a friend rather than a foe. Where does such T-cell “training” take place?
In the intestinal tract, specifically the lower end of the small intestine, which is rich in collections of immune tissue called Peyer’s patches. Peyer’s patches act as “training centers” for T-cells, exposing them to all sorts of molecular shapes that are natural components of the food we eat. In that fashion, we desensitize our immune systems and develop a natural tolerance to new foods without having constant allergic or inflammatory reactions.
So, by providing native collagen of the right 3-dimensional structure to the digestive tract, rather than to the bloodstream directly, we can “educate” our T-cells to ignore collagen when they encounter it in joints. Scientists say that this enables people to develop oral tolerance to collagen.
And oral tolerance to collagen powerfully suppresses joint inflammation, as has been shown in numerous laboratory studies. Oral administration of soluble type II collagen even prevents arthritis induced experimentally by collagen injections.
But not just any collagen works. Typical commercial processing causes collagen to become denatured, uncoiling from its normal helical shape and losing its 3-dimensional structure. Denatured collagen has no beneficial effects on joint inflammation.
A more natural form of collagen, called undenatured type II collagen, or UC-II®, has recently been developed. UC-II® is a highly effective product derived from chicken breast cartilage, a rich source of natural collagen. UC-II® retains its original 3-dimensional molecular structure, keeping it recognizable by T-cells in Peyer’s patches. And UC-II is robust enough to survive the harsh conditions in the stomach and small intestine, arriving at Peyer’s patches with its molecules intact.
It seems the therapy tackles the rheumatic disease at its root cause.
I believe that, besides for rheuma, this is a promising path for an effective medication for diabetes/MS that 're-learns' our immune system at its very root, that is in the gut... and that may become a useful complementary medicinal therapy to diet, antibiotics, gut flora transplants and the like.
I have re-adapted the concept in the first posting on pg 1.