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Inusah S, Sormani MP, Cofield SS, Aban IB, Musani SK, Srinivasasainagendra V, Cutter GR. (2010) Assessing changes in relapse rates in multiple sclerosis. Multiple Sclerosis 16 (12):1414-1421
Inusah et al report a decline in the MS relapse rate in patients recruited to trials. This decrease was seen in placebo and treatment arms. Relapse rate was negatively associated with the year of publication. This may be because patients with more active disease are increasingly opting for established treatments.
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