certain anaesthetics drain vitamin b12 which could have neuropathic consequences. i have not personally had relapses yet so i could not say for sure, but i definitely had my initial dx attack after a painful crash snowboarding. i don't really think it was the pain itself, i think it was that the trauma aggravated pre-existing spinal cord injury resulting in what seems, 5 years later, to be permanent damage.
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com