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Injection of interferon-beta in the morning decreases flu-like syndrome in MS patients



Abstract

Background
Although it is recommended that interferon-beta (IFNβ) injections be administered in the evening, it is possible that morning injections could more effectively decrease interleukin 6 secretion.

Methods
This study evaluated the effects of switching from an evening injection of IFNβ to a morning injection on the intensity of flu-like syndrome in patients with multiple sclerosis (MS). We performed an intervention study that consisted of a quantitative evaluation of IFNβ-related flu-like syndrome in a cohort of 105 MS patients. Patients with persistent flu-like reactions who injected IFNβ in the evening were encouraged to switch to morning injections. After one month, we evaluated various quantitative and qualitative changes (e.g., severity of flu-like syndrome, sleep quality, antipyretic drug use).... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1763

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Squiffy's House of Fun - Laughter for Multiple Sclerosis

no matter what time of the day i inject it still keeps me awake all night.

I often take an actifed tablet and find I sleep like a baby

http://en.wikipedia.org/wiki/Actifed