Interferon-beta in the morning decreases flu-like symptoms

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Interferon-beta in the morning decreases flu-like symptoms

Postby MSUK » Thu Apr 14, 2011 2:10 am

Injection of interferon-beta in the morning decreases flu-like syndrome in MS patients

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Abstract

Background
Although it is recommended that interferon-beta (IFNβ) injections be administered in the evening, it is possible that morning injections could more effectively decrease interleukin 6 secretion.

Methods
This study evaluated the effects of switching from an evening injection of IFNβ to a morning injection on the intensity of flu-like syndrome in patients with multiple sclerosis (MS). We performed an intervention study that consisted of a quantitative evaluation of IFNβ-related flu-like syndrome in a cohort of 105 MS patients. Patients with persistent flu-like reactions who injected IFNβ in the evening were encouraged to switch to morning injections. After one month, we evaluated various quantitative and qualitative changes (e.g., severity of flu-like syndrome, sleep quality, antipyretic drug use).... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1763
MS-UK - http://www.ms-uk.org/
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rebif

Postby paul2008 » Sun Apr 17, 2011 8:01 am

no matter what time of the day i inject it still keeps me awake all night.
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Re: rebif

Postby mrbarlow » Sun Apr 17, 2011 11:43 am

paul2008 wrote:no matter what time of the day i inject it still keeps me awake all night.


I often take an actifed tablet and find I sleep like a baby

http://en.wikipedia.org/wiki/Actifed
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